Deconjugating taurocholic acid with Bifidobacterium to mitigate obesity-driven cancer progression by restoring CD8+ T-cell infiltration

Abstract Obesity is linked to an increased cancer risk, and probiotics show promise in weight management. Here, we elucidate the precise mechanisms through which the probiotic Bifidobacterium breve (B. breve) modulates the immune response in obesity-associated tumours utilizing a Hepa1-6 cell-bearin...

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Bibliographic Details
Main Authors: Ruoshui Yuan, Yuke Li, Yifei Wang, Qingxiang Li, Chuanbin Guo, Lin Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-025-00809-4
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