First data on cholesterol metabolism in Ornithodoros argasid ticks: Molecular and functional characterization of the N-terminal domain of Niemann-Pick C1 proteins

Cholesterol is a molecule vital for tick physiology, but ticks cannot synthesize it and rely on dietary cholesterol. Therefore, tick proteins involved in cholesterol absorption and transport, such as the Niemann-Pick type C1 domain-containing (NPC1) proteins, are promising targets for anti-tick vacc...

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Bibliographic Details
Main Authors: Lucía de Dios-Blázquez, Ana Laura Cano-Argüelles, Ricardo Pérez-Sánchez, María González-Sánchez, Ana Oleaga
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Ticks and Tick-Borne Diseases
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Online Access:http://www.sciencedirect.com/science/article/pii/S1877959X2400075X
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