Inhibitory Effects of Ketamine on Lipopolysaccharide-Induced Microglial Activation
Microglia activated in response to brain injury release neurotoxic factors including nitric oxide (NO) and proinflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). Ketamine, an anesthetic induction agent, is generally reserved for use in patients with severe hyp...
Saved in:
| Main Authors: | Yi Chang, Jie-Jen Lee, Cheng-Ying Hsieh, George Hsiao, Duen-Suey Chou, Joen-Rong Sheu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2009-01-01
|
| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2009/705379 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Modulation of ER Stress and Inflammation by S-Ketamine, R-Ketamine, and Their Metabolites in Human Microglial Cells: Insights into Novel Targets for Depression Therapy
by: Marta Jóźwiak-Bębenista, et al.
Published: (2025-06-01) -
Andrographolide Inhibits Nuclear Factor-κB Activation through JNK-Akt-p65 Signaling Cascade in Tumor Necrosis Factor-α-Stimulated Vascular Smooth Muscle Cells
by: Yu-Ying Chen, et al.
Published: (2014-01-01) -
Extract of Antrodia camphorata Exerts Neuroprotection against Embolic Stroke in Rats without Causing the Risk of Hemorrhagic Incidence
by: Ye-Ming Lee, et al.
Published: (2014-01-01) -
S‐ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide‐Induced Depression Via Targeting SIRT2
by: Cong Lin, et al.
Published: (2025-06-01) -
Reawakening inflammation in the chronically injured spinal cord using lipopolysaccharide induces diverse microglial states
by: Rebecca K. John, et al.
Published: (2025-02-01)