Developing Heterogeneous Porous 3D-Printed SiO<sub>2</sub>-Pd-K<sub>2</sub>SiO<sub>3</sub> Monolithic Catalyst via Surface MOF Growth and Pyrolysis for the Synthesis of Antitumoral Isatins

Developing Heterogeneous Porous 3D-Printed SiO<sub>2</sub>-Pd-K<sub>2</sub>SiO<sub>3</sub> Monolithic Catalyst via Surface MOF Growth and Pyrolysis for the Synthesis of Antitumoral Isatins

<b>Background/Objectives</b>: The isatin nucleus is a privileged scaffold in drug discovery, particularly due to its proven relevance in anticancer research. Developing reusable heterogeneous 3D catalysts for drug synthesis represents a critical challenge in both industrial and academic...

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Bibliographic Details
Main Authors: Alexandrina Druta, Rania Bouhmala, Teqwa Ragdi, Mariangel Luna, Manuel Bañobre-López, Christian F. Masaguer, Manuel Amorín, Silvia Barbosa, Pablo Taboada, Alberto Coelho
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Pharmaceutics
Subjects:
heterogeneous catalysis
monolithic catalysts
3D printing
isatins
HeLa
MCF-7
Online Access:https://www.mdpi.com/1999-4923/17/4/505
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