Determining the Optimal Thermodynamic Conditions of Ternary Systems Containing (CO2, Solvent, 5-Fluorouracil) in the GAS Process

One of the methods to reduce the particle size is the GAS method. In this method, the solute and antisolvent should be dissolved well in a solvent. But the solute is not dissolved in a solvent. The aim of studying this model is to determine the phase equilibrium and thermodynamic conditions of (CO2,...

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Main Authors: M. Rahmanzadeh Derisi, N. Esfandiari
Format: Article
Language:English
Published: Iranian Association of Chemical Engineering (IAChE) 2022-03-01
Series:Iranian Journal of Chemical Engineering
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Online Access:https://www.ijche.com/article_154659_6ca2c1083f803046d6592eaa61e6dff1.pdf
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author M. Rahmanzadeh Derisi
N. Esfandiari
author_facet M. Rahmanzadeh Derisi
N. Esfandiari
author_sort M. Rahmanzadeh Derisi
collection DOAJ
description One of the methods to reduce the particle size is the GAS method. In this method, the solute and antisolvent should be dissolved well in a solvent. But the solute is not dissolved in a solvent. The aim of studying this model is to determine the phase equilibrium and thermodynamic conditions of (CO2, solvent, 5-Fluorouracil) in the GAS process. The solvents include methanol, ethanol, acetone, 1-propanol, and 1-butanol. The Peng-Robinson equation of state with a linear combination of Vidal and Michelsen mixing rules (PR-LCVM) was used for the thermodynamic modeling. The volume expansion of the binary system (CO2, solvent) and ternary system (CO2, solvent,5-Fluorouracil) at the temperature range of 313.15-319.15 K was investigated. The Pmin values for the binary system were 66.7, 69.6, 60, 73.7, and 76.8 bar respectively for methanol, ethanol, acetone, 1-propanol, and 1-butanol at 313.15 K,. The Pmin for the ternary system was also calculated. The comparison between the Pmin values of binary and ternary systems showed that for a constant temperature and a certain solvent, the calculated minimum pressure in the ternary system was greater than the same in the binary system
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spelling doaj-art-65c1dc665d7540a78f81a7fb3f6e57b82025-08-20T02:18:43ZengIranian Association of Chemical Engineering (IAChE)Iranian Journal of Chemical Engineering1735-53972008-23552022-03-0119131410.22034/ijche.2022.338671.1431154659Determining the Optimal Thermodynamic Conditions of Ternary Systems Containing (CO2, Solvent, 5-Fluorouracil) in the GAS ProcessM. Rahmanzadeh Derisi0N. Esfandiari1Department of Chemical Engineering, South Tehran Branch, Islamic Azad University, Tehran, Iran.Department of Chemical Engineering, Marvdasht Branch, Islamic Azad University, Marvdasht, IranOne of the methods to reduce the particle size is the GAS method. In this method, the solute and antisolvent should be dissolved well in a solvent. But the solute is not dissolved in a solvent. The aim of studying this model is to determine the phase equilibrium and thermodynamic conditions of (CO2, solvent, 5-Fluorouracil) in the GAS process. The solvents include methanol, ethanol, acetone, 1-propanol, and 1-butanol. The Peng-Robinson equation of state with a linear combination of Vidal and Michelsen mixing rules (PR-LCVM) was used for the thermodynamic modeling. The volume expansion of the binary system (CO2, solvent) and ternary system (CO2, solvent,5-Fluorouracil) at the temperature range of 313.15-319.15 K was investigated. The Pmin values for the binary system were 66.7, 69.6, 60, 73.7, and 76.8 bar respectively for methanol, ethanol, acetone, 1-propanol, and 1-butanol at 313.15 K,. The Pmin for the ternary system was also calculated. The comparison between the Pmin values of binary and ternary systems showed that for a constant temperature and a certain solvent, the calculated minimum pressure in the ternary system was greater than the same in the binary systemhttps://www.ijche.com/article_154659_6ca2c1083f803046d6592eaa61e6dff1.pdfgas processpeng-robinsonlcvmoptimal condition5-fluorouracil
spellingShingle M. Rahmanzadeh Derisi
N. Esfandiari
Determining the Optimal Thermodynamic Conditions of Ternary Systems Containing (CO2, Solvent, 5-Fluorouracil) in the GAS Process
Iranian Journal of Chemical Engineering
gas process
peng-robinson
lcvm
optimal condition
5-fluorouracil
title Determining the Optimal Thermodynamic Conditions of Ternary Systems Containing (CO2, Solvent, 5-Fluorouracil) in the GAS Process
title_full Determining the Optimal Thermodynamic Conditions of Ternary Systems Containing (CO2, Solvent, 5-Fluorouracil) in the GAS Process
title_fullStr Determining the Optimal Thermodynamic Conditions of Ternary Systems Containing (CO2, Solvent, 5-Fluorouracil) in the GAS Process
title_full_unstemmed Determining the Optimal Thermodynamic Conditions of Ternary Systems Containing (CO2, Solvent, 5-Fluorouracil) in the GAS Process
title_short Determining the Optimal Thermodynamic Conditions of Ternary Systems Containing (CO2, Solvent, 5-Fluorouracil) in the GAS Process
title_sort determining the optimal thermodynamic conditions of ternary systems containing co2 solvent 5 fluorouracil in the gas process
topic gas process
peng-robinson
lcvm
optimal condition
5-fluorouracil
url https://www.ijche.com/article_154659_6ca2c1083f803046d6592eaa61e6dff1.pdf
work_keys_str_mv AT mrahmanzadehderisi determiningtheoptimalthermodynamicconditionsofternarysystemscontainingco2solvent5fluorouracilinthegasprocess
AT nesfandiari determiningtheoptimalthermodynamicconditionsofternarysystemscontainingco2solvent5fluorouracilinthegasprocess