Determining the Optimal Thermodynamic Conditions of Ternary Systems Containing (CO2, Solvent, 5-Fluorouracil) in the GAS Process
One of the methods to reduce the particle size is the GAS method. In this method, the solute and antisolvent should be dissolved well in a solvent. But the solute is not dissolved in a solvent. The aim of studying this model is to determine the phase equilibrium and thermodynamic conditions of (CO2,...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Iranian Association of Chemical Engineering (IAChE)
2022-03-01
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| Series: | Iranian Journal of Chemical Engineering |
| Subjects: | |
| Online Access: | https://www.ijche.com/article_154659_6ca2c1083f803046d6592eaa61e6dff1.pdf |
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| Summary: | One of the methods to reduce the particle size is the GAS method. In this method, the solute and antisolvent should be dissolved well in a solvent. But the solute is not dissolved in a solvent. The aim of studying this model is to determine the phase equilibrium and thermodynamic conditions of (CO2, solvent, 5-Fluorouracil) in the GAS process. The solvents include methanol, ethanol, acetone, 1-propanol, and 1-butanol. The Peng-Robinson equation of state with a linear combination of Vidal and Michelsen mixing rules (PR-LCVM) was used for the thermodynamic modeling. The volume expansion of the binary system (CO2, solvent) and ternary system (CO2, solvent,5-Fluorouracil) at the temperature range of 313.15-319.15 K was investigated. The Pmin values for the binary system were 66.7, 69.6, 60, 73.7, and 76.8 bar respectively for methanol, ethanol, acetone, 1-propanol, and 1-butanol at 313.15 K,. The Pmin for the ternary system was also calculated. The comparison between the Pmin values of binary and ternary systems showed that for a constant temperature and a certain solvent, the calculated minimum pressure in the ternary system was greater than the same in the binary system |
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| ISSN: | 1735-5397 2008-2355 |