Early-onset difficult-to-treat rheumatoid arthritis: proposal of data-driven predictors and temporal threshold

Early-onset difficult-to-treat rheumatoid arthritis: proposal of data-driven predictors and temporal threshold

Abstract Background While risk factors for difficult-to-treat rheumatoid arthritis (D2TRA) have been studied in recent years, no studies have determined if there are differences between early and late developers of D2TRA. This study investigates whether patients can be classified by time to D2TRA de...

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Main Authors: Pablo Rodriguez-Merlos, Jose Luis Cabrera-Alarcón, Virginia Ruiz-Esquide, Chafik Alejandro Chacur, Raimon Sanmartí, Eugenio De Miguel-Mendieta, Jose María Álvaro-Gracia, Alejandro Balsa, Chamaida Plasencia-Rodríguez, Marta Novella-Navarro
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Arthritis Research & Therapy
Online Access:https://doi.org/10.1186/s13075-025-03621-9
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