Fatal paraphenylenediamine poisoning due to black henna
Paraphenylenediamine (PPD) is an oxidative chemical allergen that can cause hypersensitivity reactions. PPD intoxication could cause severe systemic adverse effects like acute renal failure, rhabdomyolysis and multiple organ failure. In this text we present a 9 year-old female patient who dev...
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| Format: | Article |
| Language: | English |
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Hacettepe University Institute of Child Health
2016-06-01
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| Series: | The Turkish Journal of Pediatrics |
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| Online Access: | https://turkjpediatr.org/article/view/1115 |
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| author | Güntülü Şık Agop Çıtak |
| author_facet | Güntülü Şık Agop Çıtak |
| author_sort | Güntülü Şık |
| collection | DOAJ |
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Paraphenylenediamine (PPD) is an oxidative chemical allergen that can cause hypersensitivity reactions. PPD intoxication could cause severe systemic adverse effects like acute renal failure, rhabdomyolysis and multiple organ failure. In this text we present a 9 year-old female patient who developed multiple organ failure and cardiac arrhythmia as a result of extensive application of PPD added to henna to the skin. Plasma exchange (PE) and continuous venovenous hemodiafiltration (CVVHDF) were started. The patient died on day 4 after developing ventricular fibrillation that was resistant to antiarrhythmic treatment and defibrillation. In summary, the most commonly seen clinical signs in PPD intoxication are cervical, upper respiratory and muscle edema, intravascular hemolysis, rhabdomyolysis, severe cardiac arrhythmias and acute renal failure. These symptoms would be suggestive of PPD poisoning.
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| format | Article |
| id | doaj-art-65a6789e6d484463a330040500d5da17 |
| institution | DOAJ |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2016-06-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-65a6789e6d484463a330040500d5da172025-08-20T03:00:54ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212016-06-0158310.24953/turkjped.2016.03.012Fatal paraphenylenediamine poisoning due to black hennaGüntülü Şık0Agop Çıtak1Pediatric Intensive Care Unit, Department of Pediatrics, Istanbul University Faculty of Medicine, İstanbul, Turkey.Pediatric Intensive Care Unit, Department of Pediatrics, Istanbul University Faculty of Medicine, İstanbul, Turkey. Paraphenylenediamine (PPD) is an oxidative chemical allergen that can cause hypersensitivity reactions. PPD intoxication could cause severe systemic adverse effects like acute renal failure, rhabdomyolysis and multiple organ failure. In this text we present a 9 year-old female patient who developed multiple organ failure and cardiac arrhythmia as a result of extensive application of PPD added to henna to the skin. Plasma exchange (PE) and continuous venovenous hemodiafiltration (CVVHDF) were started. The patient died on day 4 after developing ventricular fibrillation that was resistant to antiarrhythmic treatment and defibrillation. In summary, the most commonly seen clinical signs in PPD intoxication are cervical, upper respiratory and muscle edema, intravascular hemolysis, rhabdomyolysis, severe cardiac arrhythmias and acute renal failure. These symptoms would be suggestive of PPD poisoning. https://turkjpediatr.org/article/view/1115hemodiafiltrationhennaparaphenylenediaminepediatric intensive careplasma exchange |
| spellingShingle | Güntülü Şık Agop Çıtak Fatal paraphenylenediamine poisoning due to black henna The Turkish Journal of Pediatrics hemodiafiltration henna paraphenylenediamine pediatric intensive care plasma exchange |
| title | Fatal paraphenylenediamine poisoning due to black henna |
| title_full | Fatal paraphenylenediamine poisoning due to black henna |
| title_fullStr | Fatal paraphenylenediamine poisoning due to black henna |
| title_full_unstemmed | Fatal paraphenylenediamine poisoning due to black henna |
| title_short | Fatal paraphenylenediamine poisoning due to black henna |
| title_sort | fatal paraphenylenediamine poisoning due to black henna |
| topic | hemodiafiltration henna paraphenylenediamine pediatric intensive care plasma exchange |
| url | https://turkjpediatr.org/article/view/1115 |
| work_keys_str_mv | AT guntulusık fatalparaphenylenediaminepoisoningduetoblackhenna AT agopcıtak fatalparaphenylenediaminepoisoningduetoblackhenna |