Determination of the New SNP g.939A>G of the TYR Gene in Abnormal Coat Color in Bali Cattle
This study aimed to assess the presence of single nucleotide polymorphisms (SNPs) in the exon 1 region of the tyrosinase (TYR) gene in Bali cattle with abnormal coat color. This study analyzed 43 Bali cattle, 26 individuals with typical or standard coat color, and 17 individuals with albinism. The g...
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Fakultas Peternakan Universitas Brawijaya
2024-04-01
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| Series: | Jurnal Ilmu-Ilmu Peternakan |
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| Online Access: | https://jiip.ub.ac.id/index.php/jiip/article/view/2866 |
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| author | Kholijah Mokhmad Fakhrul Ulum Sri Darwati Ronny Rachman Noor Jakaria |
| author_facet | Kholijah Mokhmad Fakhrul Ulum Sri Darwati Ronny Rachman Noor Jakaria |
| author_sort | Kholijah |
| collection | DOAJ |
| description | This study aimed to assess the presence of single nucleotide polymorphisms (SNPs) in the exon 1 region of the tyrosinase (TYR) gene in Bali cattle with abnormal coat color. This study analyzed 43 Bali cattle, 26 individuals with typical or standard coat color, and 17 individuals with albinism. The genetic diversity of the TYR gene was determined via direct sequencing and polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) techniques. The sequence data of the TYR gene were scrutinized using BioEdit and MEGA10 software to detect single nucleotide polymorphisms (SNPs) related to different types of coat color features in Bali cattle. The genetic diversity information was derived from computations performed using PopGen 1.32 software. The results showed that exon 1 of the TYR gene was affected by the new SNP g.939A>G, which is polymorphic in Bali cattle. In conclusion, the SNP c.939A>G can be further analyzed for use as a candidate-assisted selection (MAS) for abnormal coat color in Bali cattle. |
| format | Article |
| id | doaj-art-65a23cb93cf3479da5185ddcf0fb8313 |
| institution | Kabale University |
| issn | 0852-3681 2443-0765 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Fakultas Peternakan Universitas Brawijaya |
| record_format | Article |
| series | Jurnal Ilmu-Ilmu Peternakan |
| spelling | doaj-art-65a23cb93cf3479da5185ddcf0fb83132025-08-20T03:33:42ZengFakultas Peternakan Universitas BrawijayaJurnal Ilmu-Ilmu Peternakan0852-36812443-07652024-04-01341435010.21776/ub.jiip.2024.034.01.054295Determination of the New SNP g.939A>G of the TYR Gene in Abnormal Coat Color in Bali CattleKholijah0https://orcid.org/0009-0001-0700-6750Mokhmad Fakhrul Ulum1https://orcid.org/0000-0003-2092-9645Sri Darwati2https://orcid.org/0000-0002-4882-3722Ronny Rachman Noor3Jakaria4https://orcid.org/0000-0001-7921-8528Department of Animal Production and Technology, Faculty of Animal Science, IPB University, Bogor, 16680, Indonesia.Division of Reproduction and Obstetrics, School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, 16680, Indonesia.Department of Animal Production and Technology, Faculty of Animal Science, IPB University, Bogor, 16680, Indonesia.Department of Animal Production and Technology, Faculty of Animal Science, IPB University, Bogor, 16680, Indonesia.Department of Animal Production and Technology, Faculty of Animal Science, IPB University, Bogor, 16680, Indonesia.This study aimed to assess the presence of single nucleotide polymorphisms (SNPs) in the exon 1 region of the tyrosinase (TYR) gene in Bali cattle with abnormal coat color. This study analyzed 43 Bali cattle, 26 individuals with typical or standard coat color, and 17 individuals with albinism. The genetic diversity of the TYR gene was determined via direct sequencing and polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) techniques. The sequence data of the TYR gene were scrutinized using BioEdit and MEGA10 software to detect single nucleotide polymorphisms (SNPs) related to different types of coat color features in Bali cattle. The genetic diversity information was derived from computations performed using PopGen 1.32 software. The results showed that exon 1 of the TYR gene was affected by the new SNP g.939A>G, which is polymorphic in Bali cattle. In conclusion, the SNP c.939A>G can be further analyzed for use as a candidate-assisted selection (MAS) for abnormal coat color in Bali cattle.https://jiip.ub.ac.id/index.php/jiip/article/view/2866bali cattlecoat colorsnptyr gene |
| spellingShingle | Kholijah Mokhmad Fakhrul Ulum Sri Darwati Ronny Rachman Noor Jakaria Determination of the New SNP g.939A>G of the TYR Gene in Abnormal Coat Color in Bali Cattle Jurnal Ilmu-Ilmu Peternakan bali cattle coat color snp tyr gene |
| title | Determination of the New SNP g.939A>G of the TYR Gene in Abnormal Coat Color in Bali Cattle |
| title_full | Determination of the New SNP g.939A>G of the TYR Gene in Abnormal Coat Color in Bali Cattle |
| title_fullStr | Determination of the New SNP g.939A>G of the TYR Gene in Abnormal Coat Color in Bali Cattle |
| title_full_unstemmed | Determination of the New SNP g.939A>G of the TYR Gene in Abnormal Coat Color in Bali Cattle |
| title_short | Determination of the New SNP g.939A>G of the TYR Gene in Abnormal Coat Color in Bali Cattle |
| title_sort | determination of the new snp g 939a g of the tyr gene in abnormal coat color in bali cattle |
| topic | bali cattle coat color snp tyr gene |
| url | https://jiip.ub.ac.id/index.php/jiip/article/view/2866 |
| work_keys_str_mv | AT kholijah determinationofthenewsnpg939agofthetyrgeneinabnormalcoatcolorinbalicattle AT mokhmadfakhrululum determinationofthenewsnpg939agofthetyrgeneinabnormalcoatcolorinbalicattle AT sridarwati determinationofthenewsnpg939agofthetyrgeneinabnormalcoatcolorinbalicattle AT ronnyrachmannoor determinationofthenewsnpg939agofthetyrgeneinabnormalcoatcolorinbalicattle AT jakaria determinationofthenewsnpg939agofthetyrgeneinabnormalcoatcolorinbalicattle |