Lipoprotein(a) in the diagnosis of cardiovascular risk. The values of lipoprotein (a) and apolipoprotein B in the adult population of Krasnoyarsk
Aim. To study the prevalence of elevated concentrations of lipoprotein (a) (Lp(a)) and apolipoprotein B (apoB) associated with high cardiovascular risk in a random sample of the adult Krasnoyarsk population.Material and methods. Lp(a) and apoB concentrations were determined by the immunochemilumines...
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«FIRMA «SILICEA» LLC
2023-08-01
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| Series: | Российский кардиологический журнал |
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| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/5499 |
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| author | V. S. Emelyanchik O. V. Marilovtseva R. V. Khomchenkov A. M. Moiseeva A. A. Chernova E. Yu. Emelyanchik S. Yu. Nikulina A. V. Protopopov |
| author_facet | V. S. Emelyanchik O. V. Marilovtseva R. V. Khomchenkov A. M. Moiseeva A. A. Chernova E. Yu. Emelyanchik S. Yu. Nikulina A. V. Protopopov |
| author_sort | V. S. Emelyanchik |
| collection | DOAJ |
| description | Aim. To study the prevalence of elevated concentrations of lipoprotein (a) (Lp(a)) and apolipoprotein B (apoB) associated with high cardiovascular risk in a random sample of the adult Krasnoyarsk population.Material and methods. Lp(a) and apoB concentrations were determined by the immunochemiluminescent method using an automated modular Cobas 8000 platform with biochemical module c702 (Roche Diagnostic, Switzerland). We examined 263 people aged 18 to 58 who agreed to expand the standard screening by Lp(a) and apoB determination.Results. We found that high and very high levels of Lp(a) are found in 12,9% of the examined, while in women the median value was significantly higher than in men (p=0,044). In addition, 11,4% of study participants had high apoB values, regardless of sex; 3,4% of the subjects had a combination of elevated levels of ap B and Lp(a).Conclusion. Screening for Lp(a) and apoB reveals dyslipidemia associated with high cardiovascular risk in 24,3% of working-age people |
| format | Article |
| id | doaj-art-659c9ee4ca504ef0b4ef0ca71b3faa77 |
| institution | DOAJ |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| publishDate | 2023-08-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj-art-659c9ee4ca504ef0b4ef0ca71b3faa772025-08-20T03:21:18Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202023-08-0128710.15829/1560-4071-2023-54993877Lipoprotein(a) in the diagnosis of cardiovascular risk. The values of lipoprotein (a) and apolipoprotein B in the adult population of KrasnoyarskV. S. Emelyanchik0O. V. Marilovtseva1R. V. Khomchenkov2A. M. Moiseeva3A. A. Chernova4E. Yu. Emelyanchik5S. Yu. Nikulina6A. V. Protopopov7V.F. Voyno-Yasenetsky Krasnoyarsk State Medical UniversityV.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; Regional Clinical HospitalRegional Clinical HospitalV.F. Voyno-Yasenetsky Krasnoyarsk State Medical UniversityV.F. Voyno-Yasenetsky Krasnoyarsk State Medical UniversityV.F. Voyno-Yasenetsky Krasnoyarsk State Medical UniversityV.F. Voyno-Yasenetsky Krasnoyarsk State Medical UniversityV.F. Voyno-Yasenetsky Krasnoyarsk State Medical UniversityAim. To study the prevalence of elevated concentrations of lipoprotein (a) (Lp(a)) and apolipoprotein B (apoB) associated with high cardiovascular risk in a random sample of the adult Krasnoyarsk population.Material and methods. Lp(a) and apoB concentrations were determined by the immunochemiluminescent method using an automated modular Cobas 8000 platform with biochemical module c702 (Roche Diagnostic, Switzerland). We examined 263 people aged 18 to 58 who agreed to expand the standard screening by Lp(a) and apoB determination.Results. We found that high and very high levels of Lp(a) are found in 12,9% of the examined, while in women the median value was significantly higher than in men (p=0,044). In addition, 11,4% of study participants had high apoB values, regardless of sex; 3,4% of the subjects had a combination of elevated levels of ap B and Lp(a).Conclusion. Screening for Lp(a) and apoB reveals dyslipidemia associated with high cardiovascular risk in 24,3% of working-age peoplehttps://russjcardiol.elpub.ru/jour/article/view/5499lipoprotein(a)apolipoprotein bcardiovascular riskdyslipidemia screeningatherosclerosiscoronary artery diseasestandard lipid panelhyperlipoproteinemia(a)hypercholesterolemia |
| spellingShingle | V. S. Emelyanchik O. V. Marilovtseva R. V. Khomchenkov A. M. Moiseeva A. A. Chernova E. Yu. Emelyanchik S. Yu. Nikulina A. V. Protopopov Lipoprotein(a) in the diagnosis of cardiovascular risk. The values of lipoprotein (a) and apolipoprotein B in the adult population of Krasnoyarsk Российский кардиологический журнал lipoprotein(a) apolipoprotein b cardiovascular risk dyslipidemia screening atherosclerosis coronary artery disease standard lipid panel hyperlipoproteinemia(a) hypercholesterolemia |
| title | Lipoprotein(a) in the diagnosis of cardiovascular risk. The values of lipoprotein (a) and apolipoprotein B in the adult population of Krasnoyarsk |
| title_full | Lipoprotein(a) in the diagnosis of cardiovascular risk. The values of lipoprotein (a) and apolipoprotein B in the adult population of Krasnoyarsk |
| title_fullStr | Lipoprotein(a) in the diagnosis of cardiovascular risk. The values of lipoprotein (a) and apolipoprotein B in the adult population of Krasnoyarsk |
| title_full_unstemmed | Lipoprotein(a) in the diagnosis of cardiovascular risk. The values of lipoprotein (a) and apolipoprotein B in the adult population of Krasnoyarsk |
| title_short | Lipoprotein(a) in the diagnosis of cardiovascular risk. The values of lipoprotein (a) and apolipoprotein B in the adult population of Krasnoyarsk |
| title_sort | lipoprotein a in the diagnosis of cardiovascular risk the values of lipoprotein a and apolipoprotein b in the adult population of krasnoyarsk |
| topic | lipoprotein(a) apolipoprotein b cardiovascular risk dyslipidemia screening atherosclerosis coronary artery disease standard lipid panel hyperlipoproteinemia(a) hypercholesterolemia |
| url | https://russjcardiol.elpub.ru/jour/article/view/5499 |
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