Saccharomyces cervisiae ameliorative impact combined with sulfaclozine on broiler chicken oxidative status
Abstract Poultry production has expanded, and imports from other countries have surged due to the sharp growth in demand for chicken meat. The purpose of this study was to determine the effect of different doses of sulfaclozine 30%, either alone or in conjunction with Saccharomyces cerevisiae (yeast...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
|
| Series: | BMC Veterinary Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12917-025-04955-x |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849342233596133376 |
|---|---|
| author | Nahla M. Ali Mohamed K. Hussein Nady Khairy Elbarbary Zeinab-El Amgad Enas A. Noseer |
| author_facet | Nahla M. Ali Mohamed K. Hussein Nady Khairy Elbarbary Zeinab-El Amgad Enas A. Noseer |
| author_sort | Nahla M. Ali |
| collection | DOAJ |
| description | Abstract Poultry production has expanded, and imports from other countries have surged due to the sharp growth in demand for chicken meat. The purpose of this study was to determine the effect of different doses of sulfaclozine 30%, either alone or in conjunction with Saccharomyces cerevisiae (yeast), on body weight gain, biochemical markers, oxidative status, and histopathological variation in broilers’ organs. One hundred fourteen -day-old chicks were divided into five groups for this experiment (20 each). For a total of 20 days, the first group was used as a control; the second group received 30 mg/kg of sulfaclozine; the third group received 70 mg/kg; the fourth group received 1.5 g/L of Saccharomyces cerevisiae followed by 30 mg/kg of sulfaclozine; and the final group received 70 mg/kg of sulfaclozine after taken 1.5 g/L of Saccharomyces cerevisiae. Hepatic and renal functions, along with malonaldehyde levels, were much higher in the chickens that received 70 mg/kg of sulfaclozine followed by 30 mg/kg; however, total protein, albumin, and catalase levels were much lower, and signs of liver and kidney damage were seen. On the other hand, the groups that received sulfaclozine treatments subsequent Saccharomyces cerevisiae showed improved metabolic indices and a partial recovery from the histopathological change. |
| format | Article |
| id | doaj-art-6594a524fcad49a8af7625dba3f5ee30 |
| institution | Kabale University |
| issn | 1746-6148 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Veterinary Research |
| spelling | doaj-art-6594a524fcad49a8af7625dba3f5ee302025-08-20T03:43:27ZengBMCBMC Veterinary Research1746-61482025-08-0121111610.1186/s12917-025-04955-xSaccharomyces cervisiae ameliorative impact combined with sulfaclozine on broiler chicken oxidative statusNahla M. Ali0Mohamed K. Hussein1Nady Khairy Elbarbary2Zeinab-El Amgad3Enas A. Noseer4Department of Biochemistry, Faculty of Veterinary Medicine, Aswan UniversityDepartment of Food Hygiene and Control, Faculty of Veterinary Medicine, Aswan UniversityDepartment of Food Hygiene and Control, Faculty of Veterinary Medicine, Aswan UniversityGeneral Authority for Veterinary Services, Qena Veterinary DirectorateDepartment of Biochemistry, Faculty of Veterinary Medicine, Aswan UniversityAbstract Poultry production has expanded, and imports from other countries have surged due to the sharp growth in demand for chicken meat. The purpose of this study was to determine the effect of different doses of sulfaclozine 30%, either alone or in conjunction with Saccharomyces cerevisiae (yeast), on body weight gain, biochemical markers, oxidative status, and histopathological variation in broilers’ organs. One hundred fourteen -day-old chicks were divided into five groups for this experiment (20 each). For a total of 20 days, the first group was used as a control; the second group received 30 mg/kg of sulfaclozine; the third group received 70 mg/kg; the fourth group received 1.5 g/L of Saccharomyces cerevisiae followed by 30 mg/kg of sulfaclozine; and the final group received 70 mg/kg of sulfaclozine after taken 1.5 g/L of Saccharomyces cerevisiae. Hepatic and renal functions, along with malonaldehyde levels, were much higher in the chickens that received 70 mg/kg of sulfaclozine followed by 30 mg/kg; however, total protein, albumin, and catalase levels were much lower, and signs of liver and kidney damage were seen. On the other hand, the groups that received sulfaclozine treatments subsequent Saccharomyces cerevisiae showed improved metabolic indices and a partial recovery from the histopathological change.https://doi.org/10.1186/s12917-025-04955-xBroiler chickenSufaclozineSaccharomyces cervisiaeBiochemical parameterHistopathology |
| spellingShingle | Nahla M. Ali Mohamed K. Hussein Nady Khairy Elbarbary Zeinab-El Amgad Enas A. Noseer Saccharomyces cervisiae ameliorative impact combined with sulfaclozine on broiler chicken oxidative status BMC Veterinary Research Broiler chicken Sufaclozine Saccharomyces cervisiae Biochemical parameter Histopathology |
| title | Saccharomyces cervisiae ameliorative impact combined with sulfaclozine on broiler chicken oxidative status |
| title_full | Saccharomyces cervisiae ameliorative impact combined with sulfaclozine on broiler chicken oxidative status |
| title_fullStr | Saccharomyces cervisiae ameliorative impact combined with sulfaclozine on broiler chicken oxidative status |
| title_full_unstemmed | Saccharomyces cervisiae ameliorative impact combined with sulfaclozine on broiler chicken oxidative status |
| title_short | Saccharomyces cervisiae ameliorative impact combined with sulfaclozine on broiler chicken oxidative status |
| title_sort | saccharomyces cervisiae ameliorative impact combined with sulfaclozine on broiler chicken oxidative status |
| topic | Broiler chicken Sufaclozine Saccharomyces cervisiae Biochemical parameter Histopathology |
| url | https://doi.org/10.1186/s12917-025-04955-x |
| work_keys_str_mv | AT nahlamali saccharomycescervisiaeameliorativeimpactcombinedwithsulfaclozineonbroilerchickenoxidativestatus AT mohamedkhussein saccharomycescervisiaeameliorativeimpactcombinedwithsulfaclozineonbroilerchickenoxidativestatus AT nadykhairyelbarbary saccharomycescervisiaeameliorativeimpactcombinedwithsulfaclozineonbroilerchickenoxidativestatus AT zeinabelamgad saccharomycescervisiaeameliorativeimpactcombinedwithsulfaclozineonbroilerchickenoxidativestatus AT enasanoseer saccharomycescervisiaeameliorativeimpactcombinedwithsulfaclozineonbroilerchickenoxidativestatus |