Mood disorders and 5-HTR2A genetic variants – the moderator effect of inflammation on expression of affective polarity phenotype

Mood disorders and 5-HTR2A genetic variants – the moderator effect of inflammation on expression of affective polarity phenotype

Abstract Background Although repeatedly confirmed, the molecular nature of gene-environment (GxE) interactions has rarely been investigated in the clinical context of mood disorders. This study assesses the relationship between HTR2A genetic variants and the modulatory effect of inflammation in a co...

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Main Authors: Maja Pantovic-Stefanovic, Jelena Karanovic, Vladimir Jurisic, Bojana Dunjic-Kostic, Milica Nesic, Sara Dodic, Marta Gostiljac, Marija Puric, Dusanka Savic Pavicevic, Maja Ivkovic
Format: Article
Language:English
Published: BMC 2024-10-01
Series:BMC Psychiatry
Subjects:
HTR2A rs6313
Mood disorders
Unipolar depression
Bipolar disorder
Gene-environment interactions
Online Access:https://doi.org/10.1186/s12888-024-06207-y
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