In Vivo and Ex Vivo Evaluation of 1,3-Thiazolidine-2,4-Dione Derivatives as Euglycemic Agents
Thiazolidinediones (TZDs), used to treat type 2 diabetes mellitus, act as full agonists of the peroxisome proliferator-activated receptor gamma. Unfortunately, they produce adverse effects, including weight gain, hepatic toxicity, and heart failure. Our group previously reported the design, synthesi...
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Main Authors: | Diana Alemán-González-Duhart, Samuel Álvarez-Almazán, Miguel Valdes, Feliciano Tamay-Cach, Jessica Elena Mendieta-Wejebe |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-01-01
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Series: | PPAR Research |
Online Access: | http://dx.doi.org/10.1155/2021/5100531 |
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