Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental Abnormality

Background. Pregnancy with concomitant chorioangioma and placental mesenchymal dysplasia (PMD) coexisting with a normal viable fetus is very rare. The literature was reviewed to explore the incidence and genetic origin of this condition. Case. The case was first identified by prenatal ultrasonograph...

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Main Authors: Wu Qichang, Wang Wenbo, Zheng Liangkai, Kong Hui, He Xiaoqin, Sun Li, Xu Yasong
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2013/591956
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author Wu Qichang
Wang Wenbo
Zheng Liangkai
Kong Hui
He Xiaoqin
Sun Li
Xu Yasong
author_facet Wu Qichang
Wang Wenbo
Zheng Liangkai
Kong Hui
He Xiaoqin
Sun Li
Xu Yasong
author_sort Wu Qichang
collection DOAJ
description Background. Pregnancy with concomitant chorioangioma and placental mesenchymal dysplasia (PMD) coexisting with a normal viable fetus is very rare. The literature was reviewed to explore the incidence and genetic origin of this condition. Case. The case was first identified by prenatal ultrasonography, but the prenatal diagnosis only included chorioangioma. PMD was then confirmed during postnatal evaluation, which included gross and histologic examination of the placenta. The macroscopic and microscopic findings were consistent with concomitant chorioangioma and placental mesenchymal dysplasia during pregnancy. Genetic findings confirmed genetic similarity of the chorioangioma and vesicle-like villi with the fetus. Conclusions. The case represents a rare placental abnormality whose pathogenesis and molecular basis need further research. Detailed histologic and genetic analyses are essential for accurate and differential diagnosis.
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institution Kabale University
issn 2090-6684
2090-6692
language English
publishDate 2013-01-01
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series Case Reports in Obstetrics and Gynecology
spelling doaj-art-65793f9f920a4920a40c9ff9d2929f3b2025-02-03T01:11:18ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922013-01-01201310.1155/2013/591956591956Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental AbnormalityWu Qichang0Wang Wenbo1Zheng Liangkai2Kong Hui3He Xiaoqin4Sun Li5Xu Yasong6Prenatal Diagnosis Center of Xiamen’s Maternal & Child Health Care Hospital, Xiamen, Fujian 361000, ChinaPrenatal Diagnosis Center of Xiamen’s Maternal & Child Health Care Hospital, Xiamen, Fujian 361000, ChinaPrenatal Diagnosis Center of Xiamen’s Maternal & Child Health Care Hospital, Xiamen, Fujian 361000, ChinaPrenatal Diagnosis Center of Xiamen’s Maternal & Child Health Care Hospital, Xiamen, Fujian 361000, ChinaPrenatal Diagnosis Center of Xiamen’s Maternal & Child Health Care Hospital, Xiamen, Fujian 361000, ChinaPrenatal Diagnosis Center of Xiamen’s Maternal & Child Health Care Hospital, Xiamen, Fujian 361000, ChinaPrenatal Diagnosis Center of Xiamen’s Maternal & Child Health Care Hospital, Xiamen, Fujian 361000, ChinaBackground. Pregnancy with concomitant chorioangioma and placental mesenchymal dysplasia (PMD) coexisting with a normal viable fetus is very rare. The literature was reviewed to explore the incidence and genetic origin of this condition. Case. The case was first identified by prenatal ultrasonography, but the prenatal diagnosis only included chorioangioma. PMD was then confirmed during postnatal evaluation, which included gross and histologic examination of the placenta. The macroscopic and microscopic findings were consistent with concomitant chorioangioma and placental mesenchymal dysplasia during pregnancy. Genetic findings confirmed genetic similarity of the chorioangioma and vesicle-like villi with the fetus. Conclusions. The case represents a rare placental abnormality whose pathogenesis and molecular basis need further research. Detailed histologic and genetic analyses are essential for accurate and differential diagnosis.http://dx.doi.org/10.1155/2013/591956
spellingShingle Wu Qichang
Wang Wenbo
Zheng Liangkai
Kong Hui
He Xiaoqin
Sun Li
Xu Yasong
Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental Abnormality
Case Reports in Obstetrics and Gynecology
title Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental Abnormality
title_full Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental Abnormality
title_fullStr Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental Abnormality
title_full_unstemmed Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental Abnormality
title_short Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental Abnormality
title_sort pregnancy with concomitant chorioangioma and placental mesenchymal dysplasia a rare placental abnormality
url http://dx.doi.org/10.1155/2013/591956
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