Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental Abnormality
Background. Pregnancy with concomitant chorioangioma and placental mesenchymal dysplasia (PMD) coexisting with a normal viable fetus is very rare. The literature was reviewed to explore the incidence and genetic origin of this condition. Case. The case was first identified by prenatal ultrasonograph...
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Format: | Article |
Language: | English |
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Wiley
2013-01-01
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Series: | Case Reports in Obstetrics and Gynecology |
Online Access: | http://dx.doi.org/10.1155/2013/591956 |
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author | Wu Qichang Wang Wenbo Zheng Liangkai Kong Hui He Xiaoqin Sun Li Xu Yasong |
author_facet | Wu Qichang Wang Wenbo Zheng Liangkai Kong Hui He Xiaoqin Sun Li Xu Yasong |
author_sort | Wu Qichang |
collection | DOAJ |
description | Background. Pregnancy with concomitant chorioangioma and placental mesenchymal dysplasia (PMD) coexisting with a normal viable fetus is very rare. The literature was reviewed to explore the incidence and genetic origin of this condition. Case. The case was first identified by prenatal ultrasonography, but the prenatal diagnosis only included chorioangioma. PMD was then confirmed during postnatal evaluation, which included gross and histologic examination of the placenta. The macroscopic and microscopic findings were consistent with concomitant chorioangioma and placental mesenchymal dysplasia during pregnancy. Genetic findings confirmed genetic similarity of the chorioangioma and vesicle-like villi with the fetus. Conclusions. The case represents a rare placental abnormality whose pathogenesis and molecular basis need further research. Detailed histologic and genetic analyses are essential for accurate and differential diagnosis. |
format | Article |
id | doaj-art-65793f9f920a4920a40c9ff9d2929f3b |
institution | Kabale University |
issn | 2090-6684 2090-6692 |
language | English |
publishDate | 2013-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Obstetrics and Gynecology |
spelling | doaj-art-65793f9f920a4920a40c9ff9d2929f3b2025-02-03T01:11:18ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922013-01-01201310.1155/2013/591956591956Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental AbnormalityWu Qichang0Wang Wenbo1Zheng Liangkai2Kong Hui3He Xiaoqin4Sun Li5Xu Yasong6Prenatal Diagnosis Center of Xiamen’s Maternal & Child Health Care Hospital, Xiamen, Fujian 361000, ChinaPrenatal Diagnosis Center of Xiamen’s Maternal & Child Health Care Hospital, Xiamen, Fujian 361000, ChinaPrenatal Diagnosis Center of Xiamen’s Maternal & Child Health Care Hospital, Xiamen, Fujian 361000, ChinaPrenatal Diagnosis Center of Xiamen’s Maternal & Child Health Care Hospital, Xiamen, Fujian 361000, ChinaPrenatal Diagnosis Center of Xiamen’s Maternal & Child Health Care Hospital, Xiamen, Fujian 361000, ChinaPrenatal Diagnosis Center of Xiamen’s Maternal & Child Health Care Hospital, Xiamen, Fujian 361000, ChinaPrenatal Diagnosis Center of Xiamen’s Maternal & Child Health Care Hospital, Xiamen, Fujian 361000, ChinaBackground. Pregnancy with concomitant chorioangioma and placental mesenchymal dysplasia (PMD) coexisting with a normal viable fetus is very rare. The literature was reviewed to explore the incidence and genetic origin of this condition. Case. The case was first identified by prenatal ultrasonography, but the prenatal diagnosis only included chorioangioma. PMD was then confirmed during postnatal evaluation, which included gross and histologic examination of the placenta. The macroscopic and microscopic findings were consistent with concomitant chorioangioma and placental mesenchymal dysplasia during pregnancy. Genetic findings confirmed genetic similarity of the chorioangioma and vesicle-like villi with the fetus. Conclusions. The case represents a rare placental abnormality whose pathogenesis and molecular basis need further research. Detailed histologic and genetic analyses are essential for accurate and differential diagnosis.http://dx.doi.org/10.1155/2013/591956 |
spellingShingle | Wu Qichang Wang Wenbo Zheng Liangkai Kong Hui He Xiaoqin Sun Li Xu Yasong Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental Abnormality Case Reports in Obstetrics and Gynecology |
title | Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental Abnormality |
title_full | Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental Abnormality |
title_fullStr | Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental Abnormality |
title_full_unstemmed | Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental Abnormality |
title_short | Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental Abnormality |
title_sort | pregnancy with concomitant chorioangioma and placental mesenchymal dysplasia a rare placental abnormality |
url | http://dx.doi.org/10.1155/2013/591956 |
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