A global living systematic review and meta-analysis hub of emerging vaccines in pregnancy and childhood
Abstract The COVID-19 pandemic accelerated vaccine development and generated a rapidly evolving body of evidence before and after the vaccine rollout. We developed a robust online platform to efficiently synthesize this emerging information for current and future challenges. Expanding upon our inter...
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| Format: | Article |
| Language: | English |
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BMC
2025-07-01
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| Series: | Reproductive Health |
| Online Access: | https://doi.org/10.1186/s12978-025-02090-2 |
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| author | Agustín Ciapponi Ariel Bardach Mabel Berrueta Jamile Ballivian Martin Brizuela Julieta Caravario Noelia Castellana Daniel Comande Esteban Couto Agustina Mazzoni Vanesa Ortega Edward P. K. Parker Juan M. Sambade Salva Florencia Juan Pablo Smutny Katharina Stegelmann Xu Xiong Andy Stergachis Flor M. Munoz Pierre Buekens |
| author_facet | Agustín Ciapponi Ariel Bardach Mabel Berrueta Jamile Ballivian Martin Brizuela Julieta Caravario Noelia Castellana Daniel Comande Esteban Couto Agustina Mazzoni Vanesa Ortega Edward P. K. Parker Juan M. Sambade Salva Florencia Juan Pablo Smutny Katharina Stegelmann Xu Xiong Andy Stergachis Flor M. Munoz Pierre Buekens |
| author_sort | Agustín Ciapponi |
| collection | DOAJ |
| description | Abstract The COVID-19 pandemic accelerated vaccine development and generated a rapidly evolving body of evidence before and after the vaccine rollout. We developed a robust online platform to efficiently synthesize this emerging information for current and future challenges. Expanding upon our interactive living systematic review—initially focused on COVID-19— we now include chikungunya and Lassa fever (with protocols presented in this issue), Mpox, and Disease X ( https://www.safeinpregnancy.org ). We aim to continuously monitor and periodically update and disseminate high-quality data on vaccine safety, efficacy, effectiveness, and immunogenicity in pregnancy and childhood. This platform computes real-time meta-analyses and features a visualization tool to present findings in a clear and accessible manner, supporting decision-making, vaccine development pipelines, and implementation strategies worldwide. It is also designed to integrate data on a hub of emerging vaccines in pregnancy and childhood and reflects a collaborative effort among multiple organizations. |
| format | Article |
| id | doaj-art-6578bffa2fd54823930b4e62821fd224 |
| institution | Kabale University |
| issn | 1742-4755 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Reproductive Health |
| spelling | doaj-art-6578bffa2fd54823930b4e62821fd2242025-08-20T04:02:54ZengBMCReproductive Health1742-47552025-07-012211510.1186/s12978-025-02090-2A global living systematic review and meta-analysis hub of emerging vaccines in pregnancy and childhoodAgustín Ciapponi0Ariel Bardach1Mabel Berrueta2Jamile Ballivian3Martin Brizuela4Julieta Caravario5Noelia Castellana6Daniel Comande7Esteban Couto8Agustina Mazzoni9Vanesa Ortega10Edward P. K. Parker11Juan M. Sambade12Salva Florencia13Juan Pablo Smutny14Katharina Stegelmann15Xu Xiong16Andy Stergachis17Flor M. Munoz18Pierre Buekens19Argentine Cochrane Center, Institute for Clinical Effectiveness and Health PolicyCenter for Research in Epidemiology and Public Health, CONICETDepartment of Mother and Child Health, Institute for Clinical Effectiveness and Health PolicyInstitute for Clinical Effectiveness and Health PolicyInstitute for Clinical Effectiveness and Health PolicyInstitute for Clinical Effectiveness and Health PolicyInstitute for Clinical Effectiveness and Health PolicyInstitute for Clinical Effectiveness and Health PolicyInstitute for Clinical Effectiveness and Health PolicyInstitute for Clinical Effectiveness and Health PolicyInstitute for Clinical Effectiveness and Health PolicyThe Vaccine Centre, London School of Hygiene & Tropical MedicineInstitute for Clinical Effectiveness and Health PolicyInstitute for Clinical Effectiveness and Health PolicyInstitute for Clinical Effectiveness and Health PolicyInstitute for Clinical Effectiveness and Health PolicyDepartment of Epidemiology, Celia Scott Weatherhead School of Public Health and Tropical Medicine, Tulane UniversityUniversity of Washington Schools of Pharmacy and Public HealthDepartments of Pediatrics and Molecular Virology and Microbiology, Baylor College of MedicineDepartment of Epidemiology, Celia Scott Weatherhead School of Public Health and Tropical Medicine, Tulane UniversityAbstract The COVID-19 pandemic accelerated vaccine development and generated a rapidly evolving body of evidence before and after the vaccine rollout. We developed a robust online platform to efficiently synthesize this emerging information for current and future challenges. Expanding upon our interactive living systematic review—initially focused on COVID-19— we now include chikungunya and Lassa fever (with protocols presented in this issue), Mpox, and Disease X ( https://www.safeinpregnancy.org ). We aim to continuously monitor and periodically update and disseminate high-quality data on vaccine safety, efficacy, effectiveness, and immunogenicity in pregnancy and childhood. This platform computes real-time meta-analyses and features a visualization tool to present findings in a clear and accessible manner, supporting decision-making, vaccine development pipelines, and implementation strategies worldwide. It is also designed to integrate data on a hub of emerging vaccines in pregnancy and childhood and reflects a collaborative effort among multiple organizations.https://doi.org/10.1186/s12978-025-02090-2 |
| spellingShingle | Agustín Ciapponi Ariel Bardach Mabel Berrueta Jamile Ballivian Martin Brizuela Julieta Caravario Noelia Castellana Daniel Comande Esteban Couto Agustina Mazzoni Vanesa Ortega Edward P. K. Parker Juan M. Sambade Salva Florencia Juan Pablo Smutny Katharina Stegelmann Xu Xiong Andy Stergachis Flor M. Munoz Pierre Buekens A global living systematic review and meta-analysis hub of emerging vaccines in pregnancy and childhood Reproductive Health |
| title | A global living systematic review and meta-analysis hub of emerging vaccines in pregnancy and childhood |
| title_full | A global living systematic review and meta-analysis hub of emerging vaccines in pregnancy and childhood |
| title_fullStr | A global living systematic review and meta-analysis hub of emerging vaccines in pregnancy and childhood |
| title_full_unstemmed | A global living systematic review and meta-analysis hub of emerging vaccines in pregnancy and childhood |
| title_short | A global living systematic review and meta-analysis hub of emerging vaccines in pregnancy and childhood |
| title_sort | global living systematic review and meta analysis hub of emerging vaccines in pregnancy and childhood |
| url | https://doi.org/10.1186/s12978-025-02090-2 |
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