Rare huge bilateral adrenal myelolipoma confused with retroperitoneal liposarcoma

Introduction Adrenal myelolipomas are uncommon benign adrenal tumors, which mostly occur unilaterally. We describe a rare case of giant bilateral adrenal myelolipoma mistaken for retroperitoneal liposarcoma. Case presentation A 49‐year‐old man developed fever, left flank pain, and a large mass in hi...

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Main Authors: Kana Ito, Ryo Yamashita, Yuma Sakura, Hideo Shinsaka, Masafumi Nakamura, Masato Matsuzaki, Masashi Niwakawa, Tsubasa Hiraki
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:IJU Case Reports
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Online Access:https://doi.org/10.1002/iju5.12792
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author Kana Ito
Ryo Yamashita
Yuma Sakura
Hideo Shinsaka
Masafumi Nakamura
Masato Matsuzaki
Masashi Niwakawa
Tsubasa Hiraki
author_facet Kana Ito
Ryo Yamashita
Yuma Sakura
Hideo Shinsaka
Masafumi Nakamura
Masato Matsuzaki
Masashi Niwakawa
Tsubasa Hiraki
author_sort Kana Ito
collection DOAJ
description Introduction Adrenal myelolipomas are uncommon benign adrenal tumors, which mostly occur unilaterally. We describe a rare case of giant bilateral adrenal myelolipoma mistaken for retroperitoneal liposarcoma. Case presentation A 49‐year‐old man developed fever, left flank pain, and a large mass in his left abdomen. Plain computed tomography showed a 23‐cm mass with fat‐containing components in the retroperitoneal cavity, suggestive of retroperitoneal liposarcoma. A similar 9‐cm mass was observed in the right adrenal gland, suggesting adrenal metastasis. With a clinical diagnosis of retroperitoneal liposarcoma, we administered preoperative radiation therapy and performed a bilateral tumor resection. On postoperative day 9, a surgical site infection occurred, necessitating incisional drainage and the administration of intravenous antibiotics. The histopathological diagnosis was bilateral myelolipoma of the adrenal glands. Conclusion In cases of bilateral retroperitoneal tumors with a large fat component, adrenal myelolipoma should be considered in the differential diagnosis to avoid overtreatment.
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spelling doaj-art-6576d285532e47cf926263bc0aa6204c2025-08-20T02:57:40ZengWileyIJU Case Reports2577-171X2025-01-0181151810.1002/iju5.12792Rare huge bilateral adrenal myelolipoma confused with retroperitoneal liposarcomaKana Ito0Ryo Yamashita1Yuma Sakura2Hideo Shinsaka3Masafumi Nakamura4Masato Matsuzaki5Masashi Niwakawa6Tsubasa Hiraki7Division of Urology Shizuoka Cancer Center Shizuoka JapanDivision of Urology Shizuoka Cancer Center Shizuoka JapanDivision of Urology Shizuoka Cancer Center Shizuoka JapanDivision of Urology Shizuoka Cancer Center Shizuoka JapanDivision of Urology Shizuoka Cancer Center Shizuoka JapanDivision of Urology Shizuoka Cancer Center Shizuoka JapanDivision of Urology Shizuoka Cancer Center Shizuoka JapanDepartment of Diagnostic Pathology Shizuoka Cancer Center Shizuoka JapanIntroduction Adrenal myelolipomas are uncommon benign adrenal tumors, which mostly occur unilaterally. We describe a rare case of giant bilateral adrenal myelolipoma mistaken for retroperitoneal liposarcoma. Case presentation A 49‐year‐old man developed fever, left flank pain, and a large mass in his left abdomen. Plain computed tomography showed a 23‐cm mass with fat‐containing components in the retroperitoneal cavity, suggestive of retroperitoneal liposarcoma. A similar 9‐cm mass was observed in the right adrenal gland, suggesting adrenal metastasis. With a clinical diagnosis of retroperitoneal liposarcoma, we administered preoperative radiation therapy and performed a bilateral tumor resection. On postoperative day 9, a surgical site infection occurred, necessitating incisional drainage and the administration of intravenous antibiotics. The histopathological diagnosis was bilateral myelolipoma of the adrenal glands. Conclusion In cases of bilateral retroperitoneal tumors with a large fat component, adrenal myelolipoma should be considered in the differential diagnosis to avoid overtreatment.https://doi.org/10.1002/iju5.12792adrenal myelolipomacase reportdifferential diagnosisretroperitoneal liposarcomatumor
spellingShingle Kana Ito
Ryo Yamashita
Yuma Sakura
Hideo Shinsaka
Masafumi Nakamura
Masato Matsuzaki
Masashi Niwakawa
Tsubasa Hiraki
Rare huge bilateral adrenal myelolipoma confused with retroperitoneal liposarcoma
IJU Case Reports
adrenal myelolipoma
case report
differential diagnosis
retroperitoneal liposarcoma
tumor
title Rare huge bilateral adrenal myelolipoma confused with retroperitoneal liposarcoma
title_full Rare huge bilateral adrenal myelolipoma confused with retroperitoneal liposarcoma
title_fullStr Rare huge bilateral adrenal myelolipoma confused with retroperitoneal liposarcoma
title_full_unstemmed Rare huge bilateral adrenal myelolipoma confused with retroperitoneal liposarcoma
title_short Rare huge bilateral adrenal myelolipoma confused with retroperitoneal liposarcoma
title_sort rare huge bilateral adrenal myelolipoma confused with retroperitoneal liposarcoma
topic adrenal myelolipoma
case report
differential diagnosis
retroperitoneal liposarcoma
tumor
url https://doi.org/10.1002/iju5.12792
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AT hideoshinsaka rarehugebilateraladrenalmyelolipomaconfusedwithretroperitonealliposarcoma
AT masafuminakamura rarehugebilateraladrenalmyelolipomaconfusedwithretroperitonealliposarcoma
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