Anlotinib plus chemotherapy as a first-line treatment for gastrointestinal cancer patients with unresectable liver metastases: a multicohort, multicenter, exploratory trial

Anlotinib plus chemotherapy as a first-line treatment for gastrointestinal cancer patients with unresectable liver metastases: a multicohort, multicenter, exploratory trial

Abstract This multicohort phase II trial (ALTER-G-001; NCT05262335) aimed to assess the efficacy of first-line anlotinib plus chemotherapy for gastrointestinal (GI) cancer patients with unresectable liver metastases. Eligible patients with colorectal cancer (Cohort A) or noncolorectal and nonesophag...

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Bibliographic Details
Main Authors: Jun-Wei Wu, Chen-Fei Zhou, Zheng-Xiang Han, Huan Zhang, Jun Yan, Jun Chen, Chun-Bin Wang, Zhi-Quan Qin, Yong Mao, Xin-Yu Tang, Liang-Jun Zhu, Xiao-Wei Wei, Dong-Hai Cui, Xiu-Li Yang, Min Shi, Li-Qin Zhao, Jin-Ling Jiang, Wei-You Zhu, Hong-Mei Wang, Chun Wang, Ling-Jun Zhu, Jun Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2024-12-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-024-02051-4
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