Synaptic transmission from horizontal cells to cones is impaired by loss of connexin hemichannels.
In the vertebrate retina, horizontal cells generate the inhibitory surround of bipolar cells, an essential step in contrast enhancement. For the last decades, the mechanism involved in this inhibitory synaptic pathway has been a major controversy in retinal research. One hypothesis suggests that con...
Saved in:
| Main Authors: | Lauw J Klaassen, Ziyi Sun, Marvin N Steijaert, Petra Bolte, Iris Fahrenfort, Trijntje Sjoerdsma, Jan Klooster, Yvonne Claassen, Colleen R Shields, Huub M M Ten Eikelder, Ulrike Janssen-Bienhold, Georg Zoidl, Douglas G McMahon, Maarten Kamermans |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-07-01
|
| Series: | PLoS Biology |
| Online Access: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1001107&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Contribution of Connexin Hemichannels to the Pathogenesis of Acute Lung Injury
by: Shuaiwei Wang, et al.
Published: (2020-01-01) -
Connexin hemichannels and early atrophic signaling in muscle during sepsis
by: Elisa Balboa, et al.
Published: (2025-02-01) -
Mechano-activated connexin hemichannels mediate intercellular glutathione transport and support lens redox homeostasis
by: Guangyan Wang, et al.
Published: (2025-09-01) -
Connexin43 hemichannel blockade turns microglia neuroprotective and mitigates cognitive deficits in a mouse model of amyloidosis
by: Yixun Su, et al.
Published: (2025-07-01) -
Repression of Connexin26 hemichannel activity protects the barrier function of respiratory airway epithelial cells against LPS-induced alteration
by: Tina Lehrich, et al.
Published: (2025-05-01)