Kidney haemodynamical disorders in abdominal hypertension rats

Purpose: The aim of study is to analyze changes in renal blood circulation in abdominal hypertensive rats. Methods: Two groups of anesthetized male Wistar rats were examined: control group and group exposed to artificially elevated abdominal pressure. The later has been achieved by insufflations of...

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Main Authors: V. Turiyski, A. Tolekova, R. Ardasheva, N. Sirakov, K. Velkova, A. Kristev
Format: Article
Language:English
Published: Trakia University 2018-09-01
Series:Trakia Journal of Sciences
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Online Access:http://tru.uni-sz.bg/tsj/Vol.16,%20N%203,%202018/V.Turiyski.pdf
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Summary:Purpose: The aim of study is to analyze changes in renal blood circulation in abdominal hypertensive rats. Methods: Two groups of anesthetized male Wistar rats were examined: control group and group exposed to artificially elevated abdominal pressure. The later has been achieved by insufflations of air in abdominal cavity. X-ray angiographies of both groups were conducted after introduction of contrast medium. Results: The experiments have shown dramatic changes in time-related parameters of renal haemodynamics in abdominal hypertensive rats: appearance of contrast medium in kidney parenchyma before contrasting of heart and impaired synchrony in contrasting of kidneys Conclusions: Pneumoperitoneum upsets excretory function of kidneys, thus causing significant haemodynamical disorders. It could lead to further development of improper renal endocrinal and metabolic activity.
ISSN:1312-1723
1313-3551