Bortezomib Inpatient Prescribing Practices in Free-Standing Children's Hospitals in the United States.
This study is a pharmacoepidemiologic description of pediatric bortezomib use. Exposure was identified through billing codes in patients admitted to US children's hospitals that participated with the Pediatric Health Information System between 2004 and 2013. Associated information on underlying...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2016-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0151362&type=printable |
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| author | Amanda M DiNofia Elizabeth Salazar Alix E Seif Yimei Li Yuan-Shung Vera Huang Rochelle Bagatell Brian T Fisher Richard Aplenc |
| author_facet | Amanda M DiNofia Elizabeth Salazar Alix E Seif Yimei Li Yuan-Shung Vera Huang Rochelle Bagatell Brian T Fisher Richard Aplenc |
| author_sort | Amanda M DiNofia |
| collection | DOAJ |
| description | This study is a pharmacoepidemiologic description of pediatric bortezomib use. Exposure was identified through billing codes in patients admitted to US children's hospitals that participated with the Pediatric Health Information System between 2004 and 2013. Associated information on underlying diseases, demographics, institutional use, mortality, and physician type was collected. Exposure to bortezomib was identified in 314 patients. Hematologist/Oncologists prescribed half of the bortezomib used. Use increased during the study period. Inpatient volume was positively correlated with bortezomib utilization. Bortezomib use in pediatrics is increasing for a variety of diseases. Variation in use exists across institutions. Further studies are needed to characterize bortezomib's efficacy in pediatric diseases. |
| format | Article |
| id | doaj-art-65416665e0d44d1eaaef64b46cca672b |
| institution | OA Journals |
| issn | 1932-6203 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-65416665e0d44d1eaaef64b46cca672b2025-08-20T02:15:45ZengPublic Library of Science (PLoS)PLoS ONE1932-62032016-01-01113e015136210.1371/journal.pone.0151362Bortezomib Inpatient Prescribing Practices in Free-Standing Children's Hospitals in the United States.Amanda M DiNofiaElizabeth SalazarAlix E SeifYimei LiYuan-Shung Vera HuangRochelle BagatellBrian T FisherRichard AplencThis study is a pharmacoepidemiologic description of pediatric bortezomib use. Exposure was identified through billing codes in patients admitted to US children's hospitals that participated with the Pediatric Health Information System between 2004 and 2013. Associated information on underlying diseases, demographics, institutional use, mortality, and physician type was collected. Exposure to bortezomib was identified in 314 patients. Hematologist/Oncologists prescribed half of the bortezomib used. Use increased during the study period. Inpatient volume was positively correlated with bortezomib utilization. Bortezomib use in pediatrics is increasing for a variety of diseases. Variation in use exists across institutions. Further studies are needed to characterize bortezomib's efficacy in pediatric diseases.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0151362&type=printable |
| spellingShingle | Amanda M DiNofia Elizabeth Salazar Alix E Seif Yimei Li Yuan-Shung Vera Huang Rochelle Bagatell Brian T Fisher Richard Aplenc Bortezomib Inpatient Prescribing Practices in Free-Standing Children's Hospitals in the United States. PLoS ONE |
| title | Bortezomib Inpatient Prescribing Practices in Free-Standing Children's Hospitals in the United States. |
| title_full | Bortezomib Inpatient Prescribing Practices in Free-Standing Children's Hospitals in the United States. |
| title_fullStr | Bortezomib Inpatient Prescribing Practices in Free-Standing Children's Hospitals in the United States. |
| title_full_unstemmed | Bortezomib Inpatient Prescribing Practices in Free-Standing Children's Hospitals in the United States. |
| title_short | Bortezomib Inpatient Prescribing Practices in Free-Standing Children's Hospitals in the United States. |
| title_sort | bortezomib inpatient prescribing practices in free standing children s hospitals in the united states |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0151362&type=printable |
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