Efficacy of acupuncture for stroke-associated pneumonia: a systematic review and meta-analysis
ObjectivesThis study aims to systematically evaluate the efficacy of acupuncture on stroke-associated pneumonia (SAP).MethodsEnglish and Chinese databases were searched from their inception until 15 March 2024 to collect randomized controlled trials (RCTs). The risk of bias was assessed using Cochra...
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Frontiers Media S.A.
2025-03-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1440121/full |
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| author | Kaihan Su Kaihan Su Xiaoyu Wang Xiaoyu Wang ShiYin Zhang ShiYin Zhang Jiantong Wu Jiantong Wu Yuqi Chen Lianjun Yin Haunan Li Haunan Li Jingui Wang Jingui Wang |
| author_facet | Kaihan Su Kaihan Su Xiaoyu Wang Xiaoyu Wang ShiYin Zhang ShiYin Zhang Jiantong Wu Jiantong Wu Yuqi Chen Lianjun Yin Haunan Li Haunan Li Jingui Wang Jingui Wang |
| author_sort | Kaihan Su |
| collection | DOAJ |
| description | ObjectivesThis study aims to systematically evaluate the efficacy of acupuncture on stroke-associated pneumonia (SAP).MethodsEnglish and Chinese databases were searched from their inception until 15 March 2024 to collect randomized controlled trials (RCTs). The risk of bias was assessed using Cochrane collaboration tools. RevMan 5.4.0 software was used to analyze the included studies, and the Grades of Recommendations, Assessment, Development, and Evaluation (GRADE) assessment was used to evaluate the quality of the study outcomes.Results16 studies involving 1,125 patients were included in this meta-analysis. Compared with the control group, the results showed that acupuncture significantly improved the effective rate [RR = 1.20, 95% CI (1.13, 1.27), P < 0.00001] and reduced the level of white blood cells (WBC) [MD = −6.52, 95% CI (−8.31, −4.73), P < 0.00001], C reactive protein (CRP) [MD = −6.50, 95% CI (−9.97, −3.03), P = 0.0002], neutrophil percentage (Neu%) [MD = −6.66, 95% CI (−8.96, −4.36), P < 0.00001], and procalcitonin (PCT) [MD = −0.81, 95% CI (−1.21, −0.40), P < 0.0001]. Additionally, acupuncture therapy shortened the duration of coughing [MD = −3.22, 95% CI (−4.73, −1.72), P < 0.0001], duration until disappearance of rales [MD = −3.99, 95% CI (−6.44, −1.54), P = 0.001], and duration of antibiotic use [MD = −4.51, 95% CI (−5.46, −3.57), P < 0.00001]. It also reduced the clinical pulmonary infection score (CPIS) [MD = −1.71, 95% CI (−2.71, −0.71), P = 0.0008] and National Institute of Health Stroke Scale (NIHSS) [MD = −3.93, 95% CI (−5.78, −2.09), P < 0.00001]. Moreover, acupuncture therapy increased the forced vital capacity (FVC) [MD = 0.46, 95% CI (0.02, 0.89), P = 0.04] and Forced Expiratory Volume in One Second (FEV1) [MD = 0.49, 95% CI (0.14, 0.84), P = 0.006].ConclusionThis study found that acupuncture has a positive effect in treating SAP. However, owing to the low-quality evidence, more rigorous studies are needed in the coming years to confirm these findings.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023462846, identifier CRD42023462846. |
| format | Article |
| id | doaj-art-6538edf5ebd34ec38f29c9c8c56592ea |
| institution | DOAJ |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-6538edf5ebd34ec38f29c9c8c56592ea2025-08-20T02:55:29ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-03-011210.3389/fmed.2025.14401211440121Efficacy of acupuncture for stroke-associated pneumonia: a systematic review and meta-analysisKaihan Su0Kaihan Su1Xiaoyu Wang2Xiaoyu Wang3ShiYin Zhang4ShiYin Zhang5Jiantong Wu6Jiantong Wu7Yuqi Chen8Lianjun Yin9Haunan Li10Haunan Li11Jingui Wang12Jingui Wang13Department of Tuina, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaNational Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, ChinaDepartment of Tuina, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaNational Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, ChinaDepartment of Tuina, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaNational Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, ChinaDepartment of Tuina, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaNational Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, ChinaDepartment of Acupuncture and Tuina Rehabilitation, Kunshan Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Kunshan, ChinaDepartment of Rehabilitation Medicine, The Third Affiliated Hospital of Southern Medical University, Guangzhou, ChinaDepartment of Tuina, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaNational Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, ChinaDepartment of Tuina, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaNational Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, ChinaObjectivesThis study aims to systematically evaluate the efficacy of acupuncture on stroke-associated pneumonia (SAP).MethodsEnglish and Chinese databases were searched from their inception until 15 March 2024 to collect randomized controlled trials (RCTs). The risk of bias was assessed using Cochrane collaboration tools. RevMan 5.4.0 software was used to analyze the included studies, and the Grades of Recommendations, Assessment, Development, and Evaluation (GRADE) assessment was used to evaluate the quality of the study outcomes.Results16 studies involving 1,125 patients were included in this meta-analysis. Compared with the control group, the results showed that acupuncture significantly improved the effective rate [RR = 1.20, 95% CI (1.13, 1.27), P < 0.00001] and reduced the level of white blood cells (WBC) [MD = −6.52, 95% CI (−8.31, −4.73), P < 0.00001], C reactive protein (CRP) [MD = −6.50, 95% CI (−9.97, −3.03), P = 0.0002], neutrophil percentage (Neu%) [MD = −6.66, 95% CI (−8.96, −4.36), P < 0.00001], and procalcitonin (PCT) [MD = −0.81, 95% CI (−1.21, −0.40), P < 0.0001]. Additionally, acupuncture therapy shortened the duration of coughing [MD = −3.22, 95% CI (−4.73, −1.72), P < 0.0001], duration until disappearance of rales [MD = −3.99, 95% CI (−6.44, −1.54), P = 0.001], and duration of antibiotic use [MD = −4.51, 95% CI (−5.46, −3.57), P < 0.00001]. It also reduced the clinical pulmonary infection score (CPIS) [MD = −1.71, 95% CI (−2.71, −0.71), P = 0.0008] and National Institute of Health Stroke Scale (NIHSS) [MD = −3.93, 95% CI (−5.78, −2.09), P < 0.00001]. Moreover, acupuncture therapy increased the forced vital capacity (FVC) [MD = 0.46, 95% CI (0.02, 0.89), P = 0.04] and Forced Expiratory Volume in One Second (FEV1) [MD = 0.49, 95% CI (0.14, 0.84), P = 0.006].ConclusionThis study found that acupuncture has a positive effect in treating SAP. However, owing to the low-quality evidence, more rigorous studies are needed in the coming years to confirm these findings.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023462846, identifier CRD42023462846.https://www.frontiersin.org/articles/10.3389/fmed.2025.1440121/fullacupuncturestroke-associated pneumoniameta-analysissystematic reviewSAP |
| spellingShingle | Kaihan Su Kaihan Su Xiaoyu Wang Xiaoyu Wang ShiYin Zhang ShiYin Zhang Jiantong Wu Jiantong Wu Yuqi Chen Lianjun Yin Haunan Li Haunan Li Jingui Wang Jingui Wang Efficacy of acupuncture for stroke-associated pneumonia: a systematic review and meta-analysis Frontiers in Medicine acupuncture stroke-associated pneumonia meta-analysis systematic review SAP |
| title | Efficacy of acupuncture for stroke-associated pneumonia: a systematic review and meta-analysis |
| title_full | Efficacy of acupuncture for stroke-associated pneumonia: a systematic review and meta-analysis |
| title_fullStr | Efficacy of acupuncture for stroke-associated pneumonia: a systematic review and meta-analysis |
| title_full_unstemmed | Efficacy of acupuncture for stroke-associated pneumonia: a systematic review and meta-analysis |
| title_short | Efficacy of acupuncture for stroke-associated pneumonia: a systematic review and meta-analysis |
| title_sort | efficacy of acupuncture for stroke associated pneumonia a systematic review and meta analysis |
| topic | acupuncture stroke-associated pneumonia meta-analysis systematic review SAP |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2025.1440121/full |
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