Altered Interferon Responses in Tuberculosis Patients with Type II Diabetes: Implications for Increased Disease Susceptibility

Altered Interferon Responses in Tuberculosis Patients with Type II Diabetes: Implications for Increased Disease Susceptibility

BACKGROUND: Individuals with type 2 diabetes are three times more likely to develop active tuberculosis (TB) after infection compared to those without diabetes. The mechanisms behind this increased risk remain unclear but may involve abnormal immune responses, including enhanced pro-inflammatory act...

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Bibliographic Details
Main Authors: Nofri Rahmadika, Jackie M Cliff, Ji Sook Lee
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Tuberculosis
type-2 diabetes mellitus
type-1 interferon
type-2 interferon
PBMC
BCG
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716524003527
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