Research progress on serological and clinical diagnostic assays of porcine epidemic diarrhea virus
Porcine epidemic diarrhea virus (PEDV) is a causative agent of acute, highly contagious porcine epidemic diarrhea (PED). It infects pigs of all ages and results in high mortality rates particularly in suckling piglets. Current vaccines can not provide efficient protection to infected piglets. Thus,...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Zhejiang University Press
2018-03-01
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| Series: | 浙江大学学报. 农业与生命科学版 |
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| Online Access: | https://www.academax.com/doi/10.3785/j.issn.1008-9209.2018.03.122 |
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| _version_ | 1849706530573647872 |
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| author | LEI Ximei YANG Yongle XU Shuya ZHAO Pengwei WANG Bin HUANG Yaowei |
| author_facet | LEI Ximei YANG Yongle XU Shuya ZHAO Pengwei WANG Bin HUANG Yaowei |
| author_sort | LEI Ximei |
| collection | DOAJ |
| description | Porcine epidemic diarrhea virus (PEDV) is a causative agent of acute, highly contagious porcine epidemic diarrhea (PED). It infects pigs of all ages and results in high mortality rates particularly in suckling piglets. Current vaccines can not provide efficient protection to infected piglets. Thus, developing safer and more efficacious vaccines is fundamental to the control of PEDV. Meanwhile, it is of significance in establishing sensitive and efficient serological assays for clinical diagnosis of PEDV infection as well as the surveillance and evaluation of humoral responses at post-vaccination. In this review, we summarized the current serological assays and discussed the antibody kinetics at post-infection or vaccination, aiming to provide references to the diagnoses and control of PEDV. |
| format | Article |
| id | doaj-art-652a30bf71ba45f2bb75051dc0c49f1f |
| institution | DOAJ |
| issn | 1008-9209 2097-5155 |
| language | English |
| publishDate | 2018-03-01 |
| publisher | Zhejiang University Press |
| record_format | Article |
| series | 浙江大学学报. 农业与生命科学版 |
| spelling | doaj-art-652a30bf71ba45f2bb75051dc0c49f1f2025-08-20T03:16:11ZengZhejiang University Press浙江大学学报. 农业与生命科学版1008-92092097-51552018-03-014414915610.3785/j.issn.1008-9209.2018.03.12210089209Research progress on serological and clinical diagnostic assays of porcine epidemic diarrhea virusLEI XimeiYANG YongleXU ShuyaZHAO PengweiWANG BinHUANG YaoweiPorcine epidemic diarrhea virus (PEDV) is a causative agent of acute, highly contagious porcine epidemic diarrhea (PED). It infects pigs of all ages and results in high mortality rates particularly in suckling piglets. Current vaccines can not provide efficient protection to infected piglets. Thus, developing safer and more efficacious vaccines is fundamental to the control of PEDV. Meanwhile, it is of significance in establishing sensitive and efficient serological assays for clinical diagnosis of PEDV infection as well as the surveillance and evaluation of humoral responses at post-vaccination. In this review, we summarized the current serological assays and discussed the antibody kinetics at post-infection or vaccination, aiming to provide references to the diagnoses and control of PEDV.https://www.academax.com/doi/10.3785/j.issn.1008-9209.2018.03.122porcine epidemic diarrhea virus (PEDV)serologyclinical diagnostic assaysvaccine |
| spellingShingle | LEI Ximei YANG Yongle XU Shuya ZHAO Pengwei WANG Bin HUANG Yaowei Research progress on serological and clinical diagnostic assays of porcine epidemic diarrhea virus 浙江大学学报. 农业与生命科学版 porcine epidemic diarrhea virus (PEDV) serology clinical diagnostic assays vaccine |
| title | Research progress on serological and clinical diagnostic assays of porcine epidemic diarrhea virus |
| title_full | Research progress on serological and clinical diagnostic assays of porcine epidemic diarrhea virus |
| title_fullStr | Research progress on serological and clinical diagnostic assays of porcine epidemic diarrhea virus |
| title_full_unstemmed | Research progress on serological and clinical diagnostic assays of porcine epidemic diarrhea virus |
| title_short | Research progress on serological and clinical diagnostic assays of porcine epidemic diarrhea virus |
| title_sort | research progress on serological and clinical diagnostic assays of porcine epidemic diarrhea virus |
| topic | porcine epidemic diarrhea virus (PEDV) serology clinical diagnostic assays vaccine |
| url | https://www.academax.com/doi/10.3785/j.issn.1008-9209.2018.03.122 |
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