An Insight into Pathway and Health Risk Assessment of Toxic Metals in Herbal Medicine

Introduction. Along with and in competition with orthodox medicines, herbal medicines have converted into a popular form of cure. While cumulative investigation reports on adverse effects by herbal drug uptake are few, systematic review along with deep insight into other relevant topics (carcinogeni...

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Main Authors: Rausan Zamir, Nazmul Islam, null Kudrat-E-Zahan, Ali Asraf, Choudhury M. Zakaria
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2022/2610852
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author Rausan Zamir
Nazmul Islam
null Kudrat-E-Zahan
Ali Asraf
Choudhury M. Zakaria
author_facet Rausan Zamir
Nazmul Islam
null Kudrat-E-Zahan
Ali Asraf
Choudhury M. Zakaria
author_sort Rausan Zamir
collection DOAJ
description Introduction. Along with and in competition with orthodox medicines, herbal medicines have converted into a popular form of cure. While cumulative investigation reports on adverse effects by herbal drug uptake are few, systematic review along with deep insight into other relevant topics (carcinogenic and noncarcinogenic risk assessment, mechanism of toxicity, and entering toxic metal from source to herbal drug) is sporadic. Methods. Therefore, existing research and their published outputs pointing safety assessment of herbal medicines in terms of toxic metals have been reviewed systematically and information synthesized thematically while suggesting mechanism of toxicity, consequence of prolong exposure, and pathway of toxic metal from source to herbal drugs. Result and Discussion. Our study suggests that most of the herbal medicines were unsafe to consume although claimed harmless. Possible pathways regarding migration of toxic metals into herbal medicine are discussed. Conclusion. There should have appropriate screening from herb collection, and manufacturing to selling of finished herbal medicine by authority concerned is backed.
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spelling doaj-art-652901f2c02f40b09eb36801b6061be32025-08-20T03:34:36ZengWileyJournal of Chemistry2090-90712022-01-01202210.1155/2022/2610852An Insight into Pathway and Health Risk Assessment of Toxic Metals in Herbal MedicineRausan Zamir0Nazmul Islam1null Kudrat-E-Zahan2Ali Asraf3Choudhury M. Zakaria4Department of ChemistryDepartment of Nutrition and Food TechnologyDepartment of ChemistryDepartment of ChemistryDepartment of ChemistryIntroduction. Along with and in competition with orthodox medicines, herbal medicines have converted into a popular form of cure. While cumulative investigation reports on adverse effects by herbal drug uptake are few, systematic review along with deep insight into other relevant topics (carcinogenic and noncarcinogenic risk assessment, mechanism of toxicity, and entering toxic metal from source to herbal drug) is sporadic. Methods. Therefore, existing research and their published outputs pointing safety assessment of herbal medicines in terms of toxic metals have been reviewed systematically and information synthesized thematically while suggesting mechanism of toxicity, consequence of prolong exposure, and pathway of toxic metal from source to herbal drugs. Result and Discussion. Our study suggests that most of the herbal medicines were unsafe to consume although claimed harmless. Possible pathways regarding migration of toxic metals into herbal medicine are discussed. Conclusion. There should have appropriate screening from herb collection, and manufacturing to selling of finished herbal medicine by authority concerned is backed.http://dx.doi.org/10.1155/2022/2610852
spellingShingle Rausan Zamir
Nazmul Islam
null Kudrat-E-Zahan
Ali Asraf
Choudhury M. Zakaria
An Insight into Pathway and Health Risk Assessment of Toxic Metals in Herbal Medicine
Journal of Chemistry
title An Insight into Pathway and Health Risk Assessment of Toxic Metals in Herbal Medicine
title_full An Insight into Pathway and Health Risk Assessment of Toxic Metals in Herbal Medicine
title_fullStr An Insight into Pathway and Health Risk Assessment of Toxic Metals in Herbal Medicine
title_full_unstemmed An Insight into Pathway and Health Risk Assessment of Toxic Metals in Herbal Medicine
title_short An Insight into Pathway and Health Risk Assessment of Toxic Metals in Herbal Medicine
title_sort insight into pathway and health risk assessment of toxic metals in herbal medicine
url http://dx.doi.org/10.1155/2022/2610852
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