Confocal Laser Endomicroscopy in the Study of Colonic Mucosa in IBD Patients: A Review
Confocal laser endomicroscopy (CLE) is one of several novel methods that provide real-time, high-resolution imaging at a micronscale via endoscopes. CLE and related technologies are often termed “virtual biopsy” as they simulate the images seen in traditional histology. Recently, the use of CLE was...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2012/525098 |
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| author | Francesca Salvatori Saverio Siciliano Francesco Maione Dario Esposito Stefania Masone Marcello Persico Giovanni D. De Palma |
| author_facet | Francesca Salvatori Saverio Siciliano Francesco Maione Dario Esposito Stefania Masone Marcello Persico Giovanni D. De Palma |
| author_sort | Francesca Salvatori |
| collection | DOAJ |
| description | Confocal laser endomicroscopy (CLE) is one of several novel methods that provide real-time, high-resolution imaging at a micronscale via endoscopes. CLE and related technologies are often termed “virtual biopsy” as they simulate the images seen in traditional histology. Recently, the use of CLE was reported in the study of colonic mucosa in patients with inflammatory bowel diseases and in particular in patients affected by ulcerative colitis. CLE has the potential to have an important role in management of IBD patients as it can be used to assess the grading of colitis and in detection of microscopic colitis in endoscopically silent segments. Moreover, CLE can be used in surveillance programs especially in high-risk patients. This report aims to evaluate the current data on the application of confocal endomicroscopy in clinical gastroenterology and particularly in the study of colonic mucosa in UC patients. |
| format | Article |
| id | doaj-art-651c1592691c4fb089d548db781096c3 |
| institution | OA Journals |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-651c1592691c4fb089d548db781096c32025-08-20T02:06:39ZengWileyGastroenterology Research and Practice1687-61211687-630X2012-01-01201210.1155/2012/525098525098Confocal Laser Endomicroscopy in the Study of Colonic Mucosa in IBD Patients: A ReviewFrancesca Salvatori0Saverio Siciliano1Francesco Maione2Dario Esposito3Stefania Masone4Marcello Persico5Giovanni D. De Palma6Department of General Surgery Geriatrics Oncology and Advanced Technology, Center of Excellence for Technical Innovation in Surgery (ITC), Section of Diagnostic and Therapeutic Endoscopy, School of Medicine and Surgery, University of Naples Federico II, 80131 Naples, ItalyDepartment of General Surgery Geriatrics Oncology and Advanced Technology, Center of Excellence for Technical Innovation in Surgery (ITC), Section of Diagnostic and Therapeutic Endoscopy, School of Medicine and Surgery, University of Naples Federico II, 80131 Naples, ItalyDepartment of General Surgery Geriatrics Oncology and Advanced Technology, Center of Excellence for Technical Innovation in Surgery (ITC), Section of Diagnostic and Therapeutic Endoscopy, School of Medicine and Surgery, University of Naples Federico II, 80131 Naples, ItalyDepartment of General Surgery Geriatrics Oncology and Advanced Technology, Center of Excellence for Technical Innovation in Surgery (ITC), Section of Diagnostic and Therapeutic Endoscopy, School of Medicine and Surgery, University of Naples Federico II, 80131 Naples, ItalyDepartment of General Surgery Geriatrics Oncology and Advanced Technology, Center of Excellence for Technical Innovation in Surgery (ITC), Section of Diagnostic and Therapeutic Endoscopy, School of Medicine and Surgery, University of Naples Federico II, 80131 Naples, ItalyDepartment of General Surgery Geriatrics Oncology and Advanced Technology, Center of Excellence for Technical Innovation in Surgery (ITC), Section of Diagnostic and Therapeutic Endoscopy, School of Medicine and Surgery, University of Naples Federico II, 80131 Naples, ItalyDepartment of General Surgery Geriatrics Oncology and Advanced Technology, Center of Excellence for Technical Innovation in Surgery (ITC), Section of Diagnostic and Therapeutic Endoscopy, School of Medicine and Surgery, University of Naples Federico II, 80131 Naples, ItalyConfocal laser endomicroscopy (CLE) is one of several novel methods that provide real-time, high-resolution imaging at a micronscale via endoscopes. CLE and related technologies are often termed “virtual biopsy” as they simulate the images seen in traditional histology. Recently, the use of CLE was reported in the study of colonic mucosa in patients with inflammatory bowel diseases and in particular in patients affected by ulcerative colitis. CLE has the potential to have an important role in management of IBD patients as it can be used to assess the grading of colitis and in detection of microscopic colitis in endoscopically silent segments. Moreover, CLE can be used in surveillance programs especially in high-risk patients. This report aims to evaluate the current data on the application of confocal endomicroscopy in clinical gastroenterology and particularly in the study of colonic mucosa in UC patients.http://dx.doi.org/10.1155/2012/525098 |
| spellingShingle | Francesca Salvatori Saverio Siciliano Francesco Maione Dario Esposito Stefania Masone Marcello Persico Giovanni D. De Palma Confocal Laser Endomicroscopy in the Study of Colonic Mucosa in IBD Patients: A Review Gastroenterology Research and Practice |
| title | Confocal Laser Endomicroscopy in the Study of Colonic Mucosa in IBD Patients: A Review |
| title_full | Confocal Laser Endomicroscopy in the Study of Colonic Mucosa in IBD Patients: A Review |
| title_fullStr | Confocal Laser Endomicroscopy in the Study of Colonic Mucosa in IBD Patients: A Review |
| title_full_unstemmed | Confocal Laser Endomicroscopy in the Study of Colonic Mucosa in IBD Patients: A Review |
| title_short | Confocal Laser Endomicroscopy in the Study of Colonic Mucosa in IBD Patients: A Review |
| title_sort | confocal laser endomicroscopy in the study of colonic mucosa in ibd patients a review |
| url | http://dx.doi.org/10.1155/2012/525098 |
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