Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice

Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice

IntroductionEimeria pragensis, an intestinal protozoa infecting mice, induces colitis and reduces goblet cell numbers in the large intestine. In the present study, we investigated the pathogenesis and the mechanisms underlying goblet cell down-regulation in the early phase of infection.MethodsMale C...

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Bibliographic Details
Main Authors: Yulia Dwi Setia, Mio Kokubo-Tanaka, Ryusei Tanaka, Akemi Yoshida, Eiji Nagayasu, Parnian Ahmadi, Ayako Yoshida, Haruhiko Maruyama
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Parasitology
Subjects:
Eimeria pragensis
goblet cell dysfunction
colitis
mucin down-regulation
mouse model
Online Access:https://www.frontiersin.org/articles/10.3389/fpara.2025.1621486/full
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