A microfluidic platform for anterior-posterior human endoderm patterning via countervailing morphogen gradients in vitro
Summary: Understanding how morphogen gradients spatially pattern tissues is a fundamental question in developmental biology but can be difficult to directly address using conventional approaches. Here, we expose hPSC-derived endoderm cells to countervailing gradients of anteriorizing and posterioriz...
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| Main Authors: | Leeya Engel, Kevin J. Liu, Kiara W. Cui, Eva L. de la Serna, Vipul T. Vachharajani, Carolyn E. Dundes, Sherry Li Zheng, Manali Begur, Kyle M. Loh, Lay Teng Ang, Alexander R. Dunn |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-03-01
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| Series: | iScience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004225000033 |
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