Recurrent Cardiac Sarcoid in a Post-Heart Transplant Patient: A Case Report
Sarcoidosis is defined by the development of granulomas, which affect virtually any organ. While the pathogenesis is poorly understood, treatment consists of immunosuppression, and in the case of cardiac sarcoid, may require a heart transplant. This report describes a patient with cardiac sarcoid wh...
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| Format: | Article |
| Language: | English |
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American College of Physicians
2024-06-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2024.0063 |
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| author | Bridget Worth Gitanjali Lobo Tamika Webb-Detiege |
| author_facet | Bridget Worth Gitanjali Lobo Tamika Webb-Detiege |
| author_sort | Bridget Worth |
| collection | DOAJ |
| description | Sarcoidosis is defined by the development of granulomas, which affect virtually any organ. While the pathogenesis is poorly understood, treatment consists of immunosuppression, and in the case of cardiac sarcoid, may require a heart transplant. This report describes a patient with cardiac sarcoid who developed a disease recurrence 11 years after heart transplantation. This manifestation in itself is rare; however, this is also the longest reported span of time before recurrence. Her disease is refractory to prednisone and mycophenolic acid. Further studies need to be conducted regarding the treatment of sarcoid recurrence, as immunosuppression is very difficult in these patients. |
| format | Article |
| id | doaj-art-650ba8b358fb44b3bbd693717416e1bf |
| institution | OA Journals |
| issn | 2767-7664 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | American College of Physicians |
| record_format | Article |
| series | Annals of Internal Medicine: Clinical Cases |
| spelling | doaj-art-650ba8b358fb44b3bbd693717416e1bf2025-08-20T02:12:57ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642024-06-013610.7326/aimcc.2024.0063Recurrent Cardiac Sarcoid in a Post-Heart Transplant Patient: A Case ReportBridget Worth0Gitanjali Lobo1Tamika Webb-Detiege21Ochsner Clinic Foundation, Department of Rheumatology, New Orleans, Louisiana1Ochsner Clinic Foundation, Department of Rheumatology, New Orleans, Louisiana1Ochsner Clinic Foundation, Department of Rheumatology, New Orleans, LouisianaSarcoidosis is defined by the development of granulomas, which affect virtually any organ. While the pathogenesis is poorly understood, treatment consists of immunosuppression, and in the case of cardiac sarcoid, may require a heart transplant. This report describes a patient with cardiac sarcoid who developed a disease recurrence 11 years after heart transplantation. This manifestation in itself is rare; however, this is also the longest reported span of time before recurrence. Her disease is refractory to prednisone and mycophenolic acid. Further studies need to be conducted regarding the treatment of sarcoid recurrence, as immunosuppression is very difficult in these patients.https://www.acpjournals.org/doi/10.7326/aimcc.2024.0063 |
| spellingShingle | Bridget Worth Gitanjali Lobo Tamika Webb-Detiege Recurrent Cardiac Sarcoid in a Post-Heart Transplant Patient: A Case Report Annals of Internal Medicine: Clinical Cases |
| title | Recurrent Cardiac Sarcoid in a Post-Heart Transplant Patient: A Case Report |
| title_full | Recurrent Cardiac Sarcoid in a Post-Heart Transplant Patient: A Case Report |
| title_fullStr | Recurrent Cardiac Sarcoid in a Post-Heart Transplant Patient: A Case Report |
| title_full_unstemmed | Recurrent Cardiac Sarcoid in a Post-Heart Transplant Patient: A Case Report |
| title_short | Recurrent Cardiac Sarcoid in a Post-Heart Transplant Patient: A Case Report |
| title_sort | recurrent cardiac sarcoid in a post heart transplant patient a case report |
| url | https://www.acpjournals.org/doi/10.7326/aimcc.2024.0063 |
| work_keys_str_mv | AT bridgetworth recurrentcardiacsarcoidinaposthearttransplantpatientacasereport AT gitanjalilobo recurrentcardiacsarcoidinaposthearttransplantpatientacasereport AT tamikawebbdetiege recurrentcardiacsarcoidinaposthearttransplantpatientacasereport |