Paradoxical Immune Responses in Non-HIV Cryptococcal Meningitis.

Paradoxical Immune Responses in Non-HIV Cryptococcal Meningitis.

The fungus Cryptococcus is a major cause of meningoencephalitis in HIV-infected as well as HIV-uninfected individuals with mortalities in developed countries of 20% and 30%, respectively. In HIV-related disease, defects in T-cell immunity are paramount, whereas there is little understanding of mecha...

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Main Authors: Anil A Panackal, Simone C Wuest, Yen-Chih Lin, Tianxia Wu, Nannan Zhang, Peter Kosa, Mika Komori, Andrew Blake, Sarah K Browne, Lindsey B Rosen, Ferry Hagen, Jacques Meis, Stuart M Levitz, Martha Quezado, Dima Hammoud, John E Bennett, Bibi Bielekova, Peter R Williamson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004884
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