Microbial Ligand Costimulation Drives Neutrophilic Steroid-Refractory Asthma.

Microbial Ligand Costimulation Drives Neutrophilic Steroid-Refractory Asthma.

Asthma is a heterogeneous disease whose etiology is poorly understood but is likely to involve innate responses to inhaled microbial components that are found in allergens. The influence of these components on pulmonary inflammation has been largely studied in the context of individual agonists, des...

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Main Authors: Sabelo Hadebe, Frank Kirstein, Kaat Fierens, Kong Chen, Rebecca A Drummond, Simon Vautier, Sara Sajaniemi, Graeme Murray, David L Williams, Pierre Redelinghuys, Todd A Reinhart, Beth A Fallert Junecko, Jay K Kolls, Bart N Lambrecht, Frank Brombacher, Gordon D Brown
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0134219&type=printable
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