Caffeine-augmented exercise as a pretreatment for locomotor and balance impairments induced by REM sleep deprivation in rats

Abstract Sleep deprivation (SD) is a common problem that can lead to various neurological disorders. This study was carried out to examine how SD impacts locomotor performance and coordination in rats. Moreover, we aimed to investigate the potential synergistic benefits of caffeine supplementation c...

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Bibliographic Details
Main Authors: Esmail Karami, Alireza Sarkaki, Yaghoob Farbood, Sadegh Moradi Vastegani
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-13760-3
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