Urban air pollution and chronic respiratory diseases in adults: insights from a cross-sectional study

ObjectivesAir pollution poses a substantial public health risk, especially in urban environments characterized by elevated levels of pollutants such as fine particulate matter (PM2.5) and nitrogen dioxide (NO2). These pollutants negatively impact respiratory health, contributing to chronic respirato...

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Main Authors: Mohammed M. Alyami, Fahad H. Balharith, Sunil Kumar Ravi, Ravi Shankar Reddy
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Public Health
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Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2025.1507882/full
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author Mohammed M. Alyami
Fahad H. Balharith
Sunil Kumar Ravi
Ravi Shankar Reddy
author_facet Mohammed M. Alyami
Fahad H. Balharith
Sunil Kumar Ravi
Ravi Shankar Reddy
author_sort Mohammed M. Alyami
collection DOAJ
description ObjectivesAir pollution poses a substantial public health risk, especially in urban environments characterized by elevated levels of pollutants such as fine particulate matter (PM2.5) and nitrogen dioxide (NO2). These pollutants negatively impact respiratory health, contributing to chronic respiratory conditions and reduced lung function. This study investigated the association between air pollution exposure and respiratory health outcomes, including the prevalence of chronic respiratory conditions and pulmonary function, in an urban population. Additionally, the study sought to identify demographic subgroups that are unprotected from the ill effects of air pollution.MethodsA cross-sectional study included a total of 1,300 adult participants recruited from outpatient pulmonary and general medicine clinics. Air pollution exposure was assessed based on residential proximity to major traffic routes and ambient levels of PM2.5 and NO2 obtained from the Riyadh air quality monitoring network. Lung function was measured using spirometry, and data on chronic respiratory conditions were collected through self-reports and medical record reviews. Multivariable logistic regression and linear regression models were used to analyze the association between air pollution exposure and respiratory outcomes, adjusting for confounders such as age, gender, smoking Status, socioeconomic Status, physical activity, and occupational exposures.ResultsHigher air pollution level exposures were significantly associated with an increased prevalence of chronic respiratory conditions (adjusted OR for high exposure: 2.45, 95% CI: 1.70–3.55, p < 0.001) and a reduction in lung function, as indicated by declines in FEV1 and FVC (adjusted FEV1 coefficient for high exposure: -0.45, 95% CI: −0.58 to −0.32, p < 0.001). Subgroup analyses revealed that older adults, males, and current smokers were particularly susceptible to the adverse effects of air pollution. Sensitivity analyses confirmed the robustness of these findings across different analytical scenarios.ConclusionThe study demonstrated a clear and significant association between higher air pollution level exposures and an increased risk of chronic respiratory conditions and reduced lung function. These findings highlight the need for specific interventions to decrease air pollution exposure, particularly in vulnerable urban populations, to mitigate the burden of respiratory diseases.
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spelling doaj-art-64f69d2a17fa48efac75c939e6690a442025-08-20T02:47:51ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-03-011310.3389/fpubh.2025.15078821507882Urban air pollution and chronic respiratory diseases in adults: insights from a cross-sectional studyMohammed M. Alyami0Fahad H. Balharith1Sunil Kumar Ravi2Ravi Shankar Reddy3Respiratory Therapy Department, Batterjee Medical College, Khamis Mushait, Saudi ArabiaRespiratory Therapy Department, Batterjee Medical College, Khamis Mushait, Saudi ArabiaDepartment of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi ArabiaDepartment of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi ArabiaObjectivesAir pollution poses a substantial public health risk, especially in urban environments characterized by elevated levels of pollutants such as fine particulate matter (PM2.5) and nitrogen dioxide (NO2). These pollutants negatively impact respiratory health, contributing to chronic respiratory conditions and reduced lung function. This study investigated the association between air pollution exposure and respiratory health outcomes, including the prevalence of chronic respiratory conditions and pulmonary function, in an urban population. Additionally, the study sought to identify demographic subgroups that are unprotected from the ill effects of air pollution.MethodsA cross-sectional study included a total of 1,300 adult participants recruited from outpatient pulmonary and general medicine clinics. Air pollution exposure was assessed based on residential proximity to major traffic routes and ambient levels of PM2.5 and NO2 obtained from the Riyadh air quality monitoring network. Lung function was measured using spirometry, and data on chronic respiratory conditions were collected through self-reports and medical record reviews. Multivariable logistic regression and linear regression models were used to analyze the association between air pollution exposure and respiratory outcomes, adjusting for confounders such as age, gender, smoking Status, socioeconomic Status, physical activity, and occupational exposures.ResultsHigher air pollution level exposures were significantly associated with an increased prevalence of chronic respiratory conditions (adjusted OR for high exposure: 2.45, 95% CI: 1.70–3.55, p < 0.001) and a reduction in lung function, as indicated by declines in FEV1 and FVC (adjusted FEV1 coefficient for high exposure: -0.45, 95% CI: −0.58 to −0.32, p < 0.001). Subgroup analyses revealed that older adults, males, and current smokers were particularly susceptible to the adverse effects of air pollution. Sensitivity analyses confirmed the robustness of these findings across different analytical scenarios.ConclusionThe study demonstrated a clear and significant association between higher air pollution level exposures and an increased risk of chronic respiratory conditions and reduced lung function. These findings highlight the need for specific interventions to decrease air pollution exposure, particularly in vulnerable urban populations, to mitigate the burden of respiratory diseases.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1507882/fullair pollutionrespiratory healthchronic respiratory conditionsspirometryurban population
spellingShingle Mohammed M. Alyami
Fahad H. Balharith
Sunil Kumar Ravi
Ravi Shankar Reddy
Urban air pollution and chronic respiratory diseases in adults: insights from a cross-sectional study
Frontiers in Public Health
air pollution
respiratory health
chronic respiratory conditions
spirometry
urban population
title Urban air pollution and chronic respiratory diseases in adults: insights from a cross-sectional study
title_full Urban air pollution and chronic respiratory diseases in adults: insights from a cross-sectional study
title_fullStr Urban air pollution and chronic respiratory diseases in adults: insights from a cross-sectional study
title_full_unstemmed Urban air pollution and chronic respiratory diseases in adults: insights from a cross-sectional study
title_short Urban air pollution and chronic respiratory diseases in adults: insights from a cross-sectional study
title_sort urban air pollution and chronic respiratory diseases in adults insights from a cross sectional study
topic air pollution
respiratory health
chronic respiratory conditions
spirometry
urban population
url https://www.frontiersin.org/articles/10.3389/fpubh.2025.1507882/full
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AT sunilkumarravi urbanairpollutionandchronicrespiratorydiseasesinadultsinsightsfromacrosssectionalstudy
AT ravishankarreddy urbanairpollutionandchronicrespiratorydiseasesinadultsinsightsfromacrosssectionalstudy