Recovery from Myalgic Encephalomyelitis/Chronic Fatigue syndrome developed after severe acute respiratory syndrome coronavirus 2 vaccination: A case report
Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a neurological adverse effect after severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vaccinations. However, clinicians do not recognize the condition well, and no case report has shown a full recovery. Cas...
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Wiley
2025-06-01
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| Series: | PCN Reports |
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| Online Access: | https://doi.org/10.1002/pcn5.70111 |
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| author | Isaku Kurotori Wataru Sasao Masahiko Abe |
| author_facet | Isaku Kurotori Wataru Sasao Masahiko Abe |
| author_sort | Isaku Kurotori |
| collection | DOAJ |
| description | Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a neurological adverse effect after severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vaccinations. However, clinicians do not recognize the condition well, and no case report has shown a full recovery. Case Presentation We present a 65‐year‐old Japanese female who experienced severe fatigue, postexertional malaise, orthostatic intolerance, and various symptoms after her third SARS‐CoV‐2 vaccination. Following thorough examinations and excluding other potential diagnoses, she met the diagnostic criteria for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The symptoms persisted for 30 months and improved ultimately with comprehensive treatment and a self‐management strategy, including pacing management, pharmacological treatments, and psychiatric interventions to support those struggling with the despair over the devastating symptoms. Conclusion This case report describes ME/CFS following the SARS‐CoV‐2 vaccination and its full recovery. It illustrates the importance of considering the differential diagnosis of psychiatric disorders and addressing the condition through psychiatric interventions. Our findings provide new insights into treating ME/CFS and the vaccination‐related adverse effects. |
| format | Article |
| id | doaj-art-64eb36c6539c44f98d0ddb8cbaad5f7d |
| institution | OA Journals |
| issn | 2769-2558 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | PCN Reports |
| spelling | doaj-art-64eb36c6539c44f98d0ddb8cbaad5f7d2025-08-20T02:22:04ZengWileyPCN Reports2769-25582025-06-0142n/an/a10.1002/pcn5.70111Recovery from Myalgic Encephalomyelitis/Chronic Fatigue syndrome developed after severe acute respiratory syndrome coronavirus 2 vaccination: A case reportIsaku Kurotori0Wataru Sasao1Masahiko Abe2Public Health, Faculty of Medicine Hokkaido University Hokkaido JapanHokkaido Prefecture Haboro Hospital Hokkaido JapanHokkaido Prefecture Haboro Hospital Hokkaido JapanAbstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a neurological adverse effect after severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vaccinations. However, clinicians do not recognize the condition well, and no case report has shown a full recovery. Case Presentation We present a 65‐year‐old Japanese female who experienced severe fatigue, postexertional malaise, orthostatic intolerance, and various symptoms after her third SARS‐CoV‐2 vaccination. Following thorough examinations and excluding other potential diagnoses, she met the diagnostic criteria for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The symptoms persisted for 30 months and improved ultimately with comprehensive treatment and a self‐management strategy, including pacing management, pharmacological treatments, and psychiatric interventions to support those struggling with the despair over the devastating symptoms. Conclusion This case report describes ME/CFS following the SARS‐CoV‐2 vaccination and its full recovery. It illustrates the importance of considering the differential diagnosis of psychiatric disorders and addressing the condition through psychiatric interventions. Our findings provide new insights into treating ME/CFS and the vaccination‐related adverse effects.https://doi.org/10.1002/pcn5.70111Myalgic Encephalomyelitis/Chronic Fatigue Syndromesevere acute respiratory syndrome coronavirus 2 vaccinationpacingpostexertional malaiseorthostatic intolerance |
| spellingShingle | Isaku Kurotori Wataru Sasao Masahiko Abe Recovery from Myalgic Encephalomyelitis/Chronic Fatigue syndrome developed after severe acute respiratory syndrome coronavirus 2 vaccination: A case report PCN Reports Myalgic Encephalomyelitis/Chronic Fatigue Syndrome severe acute respiratory syndrome coronavirus 2 vaccination pacing postexertional malaise orthostatic intolerance |
| title | Recovery from Myalgic Encephalomyelitis/Chronic Fatigue syndrome developed after severe acute respiratory syndrome coronavirus 2 vaccination: A case report |
| title_full | Recovery from Myalgic Encephalomyelitis/Chronic Fatigue syndrome developed after severe acute respiratory syndrome coronavirus 2 vaccination: A case report |
| title_fullStr | Recovery from Myalgic Encephalomyelitis/Chronic Fatigue syndrome developed after severe acute respiratory syndrome coronavirus 2 vaccination: A case report |
| title_full_unstemmed | Recovery from Myalgic Encephalomyelitis/Chronic Fatigue syndrome developed after severe acute respiratory syndrome coronavirus 2 vaccination: A case report |
| title_short | Recovery from Myalgic Encephalomyelitis/Chronic Fatigue syndrome developed after severe acute respiratory syndrome coronavirus 2 vaccination: A case report |
| title_sort | recovery from myalgic encephalomyelitis chronic fatigue syndrome developed after severe acute respiratory syndrome coronavirus 2 vaccination a case report |
| topic | Myalgic Encephalomyelitis/Chronic Fatigue Syndrome severe acute respiratory syndrome coronavirus 2 vaccination pacing postexertional malaise orthostatic intolerance |
| url | https://doi.org/10.1002/pcn5.70111 |
| work_keys_str_mv | AT isakukurotori recoveryfrommyalgicencephalomyelitischronicfatiguesyndromedevelopedaftersevereacuterespiratorysyndromecoronavirus2vaccinationacasereport AT watarusasao recoveryfrommyalgicencephalomyelitischronicfatiguesyndromedevelopedaftersevereacuterespiratorysyndromecoronavirus2vaccinationacasereport AT masahikoabe recoveryfrommyalgicencephalomyelitischronicfatiguesyndromedevelopedaftersevereacuterespiratorysyndromecoronavirus2vaccinationacasereport |