IgG4-Related Pericarditis Diagnosed by Accumulated Pericardial Effusion

IgG4-related pericarditis has rarely been reported. Here, we report a case of IgG4-related disease that presented with pericardial effusion. A 67-year-old female who presented with palpitations and chest pain was admitted because of a large amount of pericardial effusion that required drainage. The...

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Main Authors: Hirohito Sugawara, Tomokazu Takahashi, Yukishige Kimura, Azumi Matsui, Tamaki Matsumoto, Kimio Nishisato, Mitsuhiro Nishimura
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2023/9223342
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author Hirohito Sugawara
Tomokazu Takahashi
Yukishige Kimura
Azumi Matsui
Tamaki Matsumoto
Kimio Nishisato
Mitsuhiro Nishimura
author_facet Hirohito Sugawara
Tomokazu Takahashi
Yukishige Kimura
Azumi Matsui
Tamaki Matsumoto
Kimio Nishisato
Mitsuhiro Nishimura
author_sort Hirohito Sugawara
collection DOAJ
description IgG4-related pericarditis has rarely been reported. Here, we report a case of IgG4-related disease that presented with pericardial effusion. A 67-year-old female who presented with palpitations and chest pain was admitted because of a large amount of pericardial effusion that required drainage. The patient underwent pericardial drainage, and the symptoms were gradually alleviated. IgG4 levels were elevated in the serum and pericardial effusions. A biopsy specimen of 18F-FDG accumulated in the submandibular gland showed lymphocyte infiltration with IgG4-positive cells. The patient was diagnosed with IgG4-related pericarditis. Glucocorticoids resolved serological and imaging abnormalities. Prompt treatment improves the disease status.
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spelling doaj-art-64de72dda802472eae43d5ac31513d7d2025-08-20T02:06:36ZengWileyCase Reports in Cardiology2090-64122023-01-01202310.1155/2023/9223342IgG4-Related Pericarditis Diagnosed by Accumulated Pericardial EffusionHirohito Sugawara0Tomokazu Takahashi1Yukishige Kimura2Azumi Matsui3Tamaki Matsumoto4Kimio Nishisato5Mitsuhiro Nishimura6Department of CardiologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyIgG4-related pericarditis has rarely been reported. Here, we report a case of IgG4-related disease that presented with pericardial effusion. A 67-year-old female who presented with palpitations and chest pain was admitted because of a large amount of pericardial effusion that required drainage. The patient underwent pericardial drainage, and the symptoms were gradually alleviated. IgG4 levels were elevated in the serum and pericardial effusions. A biopsy specimen of 18F-FDG accumulated in the submandibular gland showed lymphocyte infiltration with IgG4-positive cells. The patient was diagnosed with IgG4-related pericarditis. Glucocorticoids resolved serological and imaging abnormalities. Prompt treatment improves the disease status.http://dx.doi.org/10.1155/2023/9223342
spellingShingle Hirohito Sugawara
Tomokazu Takahashi
Yukishige Kimura
Azumi Matsui
Tamaki Matsumoto
Kimio Nishisato
Mitsuhiro Nishimura
IgG4-Related Pericarditis Diagnosed by Accumulated Pericardial Effusion
Case Reports in Cardiology
title IgG4-Related Pericarditis Diagnosed by Accumulated Pericardial Effusion
title_full IgG4-Related Pericarditis Diagnosed by Accumulated Pericardial Effusion
title_fullStr IgG4-Related Pericarditis Diagnosed by Accumulated Pericardial Effusion
title_full_unstemmed IgG4-Related Pericarditis Diagnosed by Accumulated Pericardial Effusion
title_short IgG4-Related Pericarditis Diagnosed by Accumulated Pericardial Effusion
title_sort igg4 related pericarditis diagnosed by accumulated pericardial effusion
url http://dx.doi.org/10.1155/2023/9223342
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