Atractylenolide-I prevents abdominal aortic aneurysm formation through inhibiting inflammation

Atractylenolide-I prevents abdominal aortic aneurysm formation through inhibiting inflammation

BackgroundAbdominal aortic aneurysm (AAA) is a degenerative disease with high mortality. Chronic inflammation plays a vital role in the formation of AAA. Atractylenolide-I (ATL-I) is a major bioactive component of Rhizoma Atractylodis Macrocephalae that exerts anti-inflammatory effects in various di...

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Bibliographic Details
Main Authors: Shuxiao Chen, Xiaotian Liu, Xincheng Zhou, Weixiao Lin, Minting Liu, Haoran Ma, Keli Zhong, Qiming Ma, Chengjian Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
abdominal aortic aneurysm
atractylenolide-I
inflammation
AMPK
treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1486072/full
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