Beneficial Impact of Vaccination Against SARS-CoV-2 on the Mental Health of IPF Patients
<b>Background</b>: Depression and anxiety represent significant comorbidities in idiopathic pulmonary fibrosis (IPF) patients, affecting their quality of life. The COVID-19 pandemic has had an uneven impact on global mental health. The Hospital Anxiety and Depression Scale (HADS) constit...
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2024-11-01
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| author | Ioannis Tomos Andriana I. Papaioannou Zoe I. Daniil Ilias E. Dimeas Paraskevi Kirgou Athena Gogali Konstantinos Tatsis Ilias Papanikolaou Vasilios Tzilas Argyrios Tzouvelekis Panayiota Tsiri Paschalis Steiropoulos Pachalis Ntolios Areti Xyfteri Katerina Antoniou Emmanouil Symvoulakis Aggeliki Haritou Maria Maniati Lykourgos Kolilekas Elvira-Markella Antonogiannaki Vasiliki Apollonatou Maria Kallieri Kostas Samaras Stylianos Loukides Anna Karakatsani Demosthenes Bouros Effrosyni Manali Spyros Papiris |
| author_facet | Ioannis Tomos Andriana I. Papaioannou Zoe I. Daniil Ilias E. Dimeas Paraskevi Kirgou Athena Gogali Konstantinos Tatsis Ilias Papanikolaou Vasilios Tzilas Argyrios Tzouvelekis Panayiota Tsiri Paschalis Steiropoulos Pachalis Ntolios Areti Xyfteri Katerina Antoniou Emmanouil Symvoulakis Aggeliki Haritou Maria Maniati Lykourgos Kolilekas Elvira-Markella Antonogiannaki Vasiliki Apollonatou Maria Kallieri Kostas Samaras Stylianos Loukides Anna Karakatsani Demosthenes Bouros Effrosyni Manali Spyros Papiris |
| author_sort | Ioannis Tomos |
| collection | DOAJ |
| description | <b>Background</b>: Depression and anxiety represent significant comorbidities in idiopathic pulmonary fibrosis (IPF) patients, affecting their quality of life. The COVID-19 pandemic has had an uneven impact on global mental health. The Hospital Anxiety and Depression Scale (HADS) constitutes a validated tool to identify anxiety disorders and depression. The aim of this multicentre study was to evaluate the effect of COVID-19 vaccination on depression and anxiety in IPF patients. <b>Methods</b>: Consecutive IPF patients (median 73.5 years) who are regularly followed-up with were included in the study. Demographics, functional, and clinical were recorded. The HADS score was calculated before and one month after vaccination against COVID-19 in all participants. A Wilcoxon signed ranks test was conducted. <b>Results</b>: A total of 180 IPF patients (median 73.5 years) were included in the study. Among them, 145 patients (81%) received antifibrotic treatment. A significant reduction in HADS, both in anxiety and depression scales, was observed one month after vaccination against SARS-COV-2), independent of age, smoking, lung function impairment, and prior history of depression (<i>p</i> < 0.01). <b>Conclusions</b>: A higher Hospital Anxiety and Depression Scale score was detected before vaccination against COVID-19. It seems that vaccination also offered a beneficial effect on depression and anxiety in IPF patients, independent of age, smoking, lung function impairment, and prior history of depression. |
| format | Article |
| id | doaj-art-64d7d67626c240e7acf413ef2bf73610 |
| institution | DOAJ |
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| language | English |
| publishDate | 2024-11-01 |
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| series | Advances in Respiratory Medicine |
| spelling | doaj-art-64d7d67626c240e7acf413ef2bf736102025-08-20T02:50:56ZengMDPI AGAdvances in Respiratory Medicine2543-60312024-11-0192646647110.3390/arm92060042Beneficial Impact of Vaccination Against SARS-CoV-2 on the Mental Health of IPF PatientsIoannis Tomos0Andriana I. Papaioannou1Zoe I. Daniil2Ilias E. Dimeas3Paraskevi Kirgou4Athena Gogali5Konstantinos Tatsis6Ilias Papanikolaou7Vasilios Tzilas8Argyrios Tzouvelekis9Panayiota Tsiri10Paschalis Steiropoulos11Pachalis Ntolios12Areti Xyfteri13Katerina Antoniou14Emmanouil Symvoulakis15Aggeliki Haritou16Maria Maniati17Lykourgos Kolilekas18Elvira-Markella Antonogiannaki19Vasiliki Apollonatou20Maria Kallieri21Kostas Samaras22Stylianos Loukides23Anna Karakatsani24Demosthenes Bouros25Effrosyni Manali26Spyros Papiris275th Pulmonary Medicine Department, SOTIRIA Thoracic Diseases Hospital of Athens, 11527 Athens, GreeceFirst Academic Department of Pneumonology, SOTIRIA Thoracic Diseases Hospital of Athens, Medical School, National and Kapodistrian University of Athens, 11527 Athens, GreeceDepartment of Respiratory Medicine, Medical School, University of Thessaly, 41110 Larissa, GreeceDepartment of Respiratory Medicine, Medical School, University of Thessaly, 41110 Larissa, GreeceDepartment of Respiratory Medicine, Medical School, University of Thessaly, 41110 Larissa, GreeceDepartment of Pneumonology, Medical School, University of Ioannina, 45500 Ioannina, GreeceDepartment of Pneumonology, Medical School, University of Ioannina, 45500 Ioannina, GreecePulmonary Department, Corfu General Hospital, 49100 Corfu, Greece2nd Pulmonary Medicine Department, General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, 12462 Athens, GreeceDepartment of Respiratory Medicine, General Hospital of Patras, University of Patras, 26500 Patras, GreeceDepartment of Respiratory Medicine, General Hospital of Patras, University of Patras, 26500 Patras, GreeceDepartment of Pneumonology, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, 68100 Alexandroupolis, GreeceDepartment of Pneumonology, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, 68100 Alexandroupolis, GreecePrivate Practice, 24200 Messini, GreeceDepartment of Thoracic Medicine and Laboratory of Molecular and Cellular Pneumonology, Medical School, University of Crete, 71500 Heraklion, GreeceClinic of Social and Family Medicine, Department of Social Medicine, School of Medicine, University of Crete, 71500 Heraklion, GreecePrivate Practice, 45500 Ioannina, GreecePrivate Practice, 45500 Ioannina, Greece7th Pulmonary Department, SOTIRIA Thoracic Diseases Hospital of Athens, 15772 Athens, Greece2nd Pulmonary Medicine Department, General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece2nd Pulmonary Medicine Department, General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece2nd Pulmonary Medicine Department, General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, 12462 Athens, GreecePrivate Practice, 11527 Athens, Greece2nd Pulmonary Medicine Department, General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece2nd Pulmonary Medicine Department, General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, 12462 Athens, GreeceIatriko Medical Center and National and Kapodstrian University of Athens, 15125 Athens, Greece2nd Pulmonary Medicine Department, General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece2nd Pulmonary Medicine Department, General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece<b>Background</b>: Depression and anxiety represent significant comorbidities in idiopathic pulmonary fibrosis (IPF) patients, affecting their quality of life. The COVID-19 pandemic has had an uneven impact on global mental health. The Hospital Anxiety and Depression Scale (HADS) constitutes a validated tool to identify anxiety disorders and depression. The aim of this multicentre study was to evaluate the effect of COVID-19 vaccination on depression and anxiety in IPF patients. <b>Methods</b>: Consecutive IPF patients (median 73.5 years) who are regularly followed-up with were included in the study. Demographics, functional, and clinical were recorded. The HADS score was calculated before and one month after vaccination against COVID-19 in all participants. A Wilcoxon signed ranks test was conducted. <b>Results</b>: A total of 180 IPF patients (median 73.5 years) were included in the study. Among them, 145 patients (81%) received antifibrotic treatment. A significant reduction in HADS, both in anxiety and depression scales, was observed one month after vaccination against SARS-COV-2), independent of age, smoking, lung function impairment, and prior history of depression (<i>p</i> < 0.01). <b>Conclusions</b>: A higher Hospital Anxiety and Depression Scale score was detected before vaccination against COVID-19. It seems that vaccination also offered a beneficial effect on depression and anxiety in IPF patients, independent of age, smoking, lung function impairment, and prior history of depression.https://www.mdpi.com/2543-6031/92/6/42mental healthdepressionanxietyIdiopathic pulmonary fibrosisvaccination against COVID-19vaccines |
| spellingShingle | Ioannis Tomos Andriana I. Papaioannou Zoe I. Daniil Ilias E. Dimeas Paraskevi Kirgou Athena Gogali Konstantinos Tatsis Ilias Papanikolaou Vasilios Tzilas Argyrios Tzouvelekis Panayiota Tsiri Paschalis Steiropoulos Pachalis Ntolios Areti Xyfteri Katerina Antoniou Emmanouil Symvoulakis Aggeliki Haritou Maria Maniati Lykourgos Kolilekas Elvira-Markella Antonogiannaki Vasiliki Apollonatou Maria Kallieri Kostas Samaras Stylianos Loukides Anna Karakatsani Demosthenes Bouros Effrosyni Manali Spyros Papiris Beneficial Impact of Vaccination Against SARS-CoV-2 on the Mental Health of IPF Patients Advances in Respiratory Medicine mental health depression anxiety Idiopathic pulmonary fibrosis vaccination against COVID-19 vaccines |
| title | Beneficial Impact of Vaccination Against SARS-CoV-2 on the Mental Health of IPF Patients |
| title_full | Beneficial Impact of Vaccination Against SARS-CoV-2 on the Mental Health of IPF Patients |
| title_fullStr | Beneficial Impact of Vaccination Against SARS-CoV-2 on the Mental Health of IPF Patients |
| title_full_unstemmed | Beneficial Impact of Vaccination Against SARS-CoV-2 on the Mental Health of IPF Patients |
| title_short | Beneficial Impact of Vaccination Against SARS-CoV-2 on the Mental Health of IPF Patients |
| title_sort | beneficial impact of vaccination against sars cov 2 on the mental health of ipf patients |
| topic | mental health depression anxiety Idiopathic pulmonary fibrosis vaccination against COVID-19 vaccines |
| url | https://www.mdpi.com/2543-6031/92/6/42 |
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