Vitamin K2 Alleviates Insulin Resistance Associated Skeletal Muscle Atrophy via the AKT/mTOR Signalling Pathway

Vitamin K2 Alleviates Insulin Resistance Associated Skeletal Muscle Atrophy via the AKT/mTOR Signalling Pathway

ABSTRACT Background Skeletal muscle atrophy and insulin resistance (IR) aggravate each other. Vitamin K2 (VK2) exhibits beneficial effects on IR, but whether it improves IR associated skeletal muscle atrophy remains insufficiently understood. This study aims to investigate the effects of VK2 on IR a...

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Bibliographic Details
Main Authors: Yingfeng Zhang, Yina Wang, Zhu Ming, Bin Li, Haitao Qi, Hongquan Xie, Guoliang Wang, Jiepeng Chen, Lili Duan, Ran Li, Ying Li
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
AKT/mTOR pathway
insulin resistance
menaquinone‐7
skeletal muscle atrophy
vitamin K2
Online Access:https://doi.org/10.1002/jcsm.13840
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