A patient-centric chest pain management approach utilizing a high sensitivity Troponin-I assay

Objective: The purpose of this study was to assess the impact of adoption of a new cardiac chest pain pathway that included hs-cTnI in the emergency department (ED) when evaluating chest pain patients. Methods: A new pathway incorporating both hs-cTnI testing (Seimens Healthineers Atellica) and risk...

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Main Authors: Abby E. Roetger, Christopher D. McKinney, De B. Winter III, Charmaine Lewis, Kristopher Swiger, Claire M. Corbett, Gregory Hall, Adam David, Austin Gratton
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Heliyon
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Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024141953
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author Abby E. Roetger
Christopher D. McKinney
De B. Winter III
Charmaine Lewis
Kristopher Swiger
Claire M. Corbett
Gregory Hall
Adam David
Austin Gratton
author_facet Abby E. Roetger
Christopher D. McKinney
De B. Winter III
Charmaine Lewis
Kristopher Swiger
Claire M. Corbett
Gregory Hall
Adam David
Austin Gratton
author_sort Abby E. Roetger
collection DOAJ
description Objective: The purpose of this study was to assess the impact of adoption of a new cardiac chest pain pathway that included hs-cTnI in the emergency department (ED) when evaluating chest pain patients. Methods: A new pathway incorporating both hs-cTnI testing (Seimens Healthineers Atellica) and risk stratification tools was developed. The impact of the new algorithm was assessed through a retrospective observational review of patients admitted to the ED with chest pain before implementation and after implementation. Before implementation, the conventional Seimens troponin Vista assay was utilized without a defined algorithmic approach. Bivariate analyses were performed comparing the time periods to determine differences in patient discharge dispositions, length of stay, outcomes, and rate of diagnostic cardiac catheterization. Results: The proportion of patients discharged from the ED increased while the proportion of patients placed in observation or admitted as in-patient decreased. Variation amongst providers regarding patient disposition decreased. The stress testing rate of patients placed in observation decreased over baseline. There was no change in 30-day MACE rate, but there was a decrease in 30-day MI rate. Conclusions: The new standardized hs-cTnI algorithm approach is safe as demonstrated by no change in 30-day MACE and is also more appropriate and efficient for patients presenting to the ED with chest pain compared to the non-standardized approach with cTnI used previously.
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spelling doaj-art-64cc9eda99a24340b9af5b1c3e8296282024-11-12T05:18:57ZengElsevierHeliyon2405-84402024-10-011020e38164A patient-centric chest pain management approach utilizing a high sensitivity Troponin-I assayAbby E. Roetger0Christopher D. McKinney1De B. Winter III2Charmaine Lewis3Kristopher Swiger4Claire M. Corbett5Gregory Hall6Adam David7Austin Gratton8Institute of Safety and Quality, Novant Health, Wilmington, N.C., USADepartment of Pathology, Novant Health New Hanover Regional Medical Center, Wilmington, N.C., USA; Corresponding author.Emergency Medicine, Novant Health New Hanover Regional Medical Center, Wilmington, N.C., USAHospital Medicine, Novant Health Inpatient Care Specialists, Novant Health New Hanover Regional Medical Center, Wilmington, N.C., USAHeart and Vascular Institute, Novant Health New Hanover Regional Medical Center, Wilmington, N.C., USAInstitute of Safety and Quality, Novant Health, Wilmington, N.C., USAAnesthesiology, Novant Health New Hanover Regional Medical Center, Wilmington, N.C., USADigital Products and Services, Novant Health, Wilmington, N.C., USAResearch Division, South East Area Health Education Center, Novant Health New Hanover Regional Medical Center, Wilmington, N.C., USAObjective: The purpose of this study was to assess the impact of adoption of a new cardiac chest pain pathway that included hs-cTnI in the emergency department (ED) when evaluating chest pain patients. Methods: A new pathway incorporating both hs-cTnI testing (Seimens Healthineers Atellica) and risk stratification tools was developed. The impact of the new algorithm was assessed through a retrospective observational review of patients admitted to the ED with chest pain before implementation and after implementation. Before implementation, the conventional Seimens troponin Vista assay was utilized without a defined algorithmic approach. Bivariate analyses were performed comparing the time periods to determine differences in patient discharge dispositions, length of stay, outcomes, and rate of diagnostic cardiac catheterization. Results: The proportion of patients discharged from the ED increased while the proportion of patients placed in observation or admitted as in-patient decreased. Variation amongst providers regarding patient disposition decreased. The stress testing rate of patients placed in observation decreased over baseline. There was no change in 30-day MACE rate, but there was a decrease in 30-day MI rate. Conclusions: The new standardized hs-cTnI algorithm approach is safe as demonstrated by no change in 30-day MACE and is also more appropriate and efficient for patients presenting to the ED with chest pain compared to the non-standardized approach with cTnI used previously.http://www.sciencedirect.com/science/article/pii/S2405844024141953High sensitivity troponinChest pain algorithmPatient outcomes
spellingShingle Abby E. Roetger
Christopher D. McKinney
De B. Winter III
Charmaine Lewis
Kristopher Swiger
Claire M. Corbett
Gregory Hall
Adam David
Austin Gratton
A patient-centric chest pain management approach utilizing a high sensitivity Troponin-I assay
Heliyon
High sensitivity troponin
Chest pain algorithm
Patient outcomes
title A patient-centric chest pain management approach utilizing a high sensitivity Troponin-I assay
title_full A patient-centric chest pain management approach utilizing a high sensitivity Troponin-I assay
title_fullStr A patient-centric chest pain management approach utilizing a high sensitivity Troponin-I assay
title_full_unstemmed A patient-centric chest pain management approach utilizing a high sensitivity Troponin-I assay
title_short A patient-centric chest pain management approach utilizing a high sensitivity Troponin-I assay
title_sort patient centric chest pain management approach utilizing a high sensitivity troponin i assay
topic High sensitivity troponin
Chest pain algorithm
Patient outcomes
url http://www.sciencedirect.com/science/article/pii/S2405844024141953
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