DNA methylation mechanisms in the maturing and ageing oocyte

DNA methylation mechanisms in the maturing and ageing oocyte

Abstract Oocyte maturation involves both nuclear and cytoplasmic processes that are critical for the acquisition of oocyte competence. Granulosa cells, surrounding the oocyte, play a pivotal role in the maturation process, with mechanisms such as cAMP signaling significantly influencing oocyte devel...

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Bibliographic Details
Main Authors: Carla Caniçais, Sara Vasconcelos, Fátima Santos, Sofia Dória, C. Joana Marques
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Epigenetics & Chromatin
Subjects:
Epigenetics
Oocyte
DNA methylation
Ageing
Genomic imprinting
Online Access:https://doi.org/10.1186/s13072-025-00600-x
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