The conserved LEM-3/Ankle1 nuclease is involved in the combinatorial regulation of meiotic recombination repair and chromosome segregation in Caenorhabditis elegans.

The conserved LEM-3/Ankle1 nuclease is involved in the combinatorial regulation of meiotic recombination repair and chromosome segregation in Caenorhabditis elegans.

Homologous recombination is essential for crossover (CO) formation and accurate chromosome segregation during meiosis. It is of considerable importance to work out how recombination intermediates are processed, leading to CO and non-crossover (NCO) outcome. Genetic analysis in budding yeast and Caen...

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Bibliographic Details
Main Authors: Ye Hong, Maria Velkova, Nicola Silva, Marlène Jagut, Viktor Scheidt, Karim Labib, Verena Jantsch, Anton Gartner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-06-01
Series:PLoS Genetics
Online Access:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pgen.1007453/2/pgen.1007453.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210222%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210222T125231Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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