Anterior and Posterior Corneal Higher-order Aberrations in Keratoconus and Pellucid Marginal Corneal Degeneration by Pentacam
Aim: To assess the changes in the anterior and posterior corneal surface aberrations in keratoconus (KC) and pellucid marginal corneal degeneration (PMCD) and compare them to age-matched normal eyes using the pentacam system. Materials and Methods: This single-center, retrospective study was carried...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Delhi Journal of Ophthalmology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/DLJO.DLJO_126_24 |
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| Summary: | Aim:
To assess the changes in the anterior and posterior corneal surface aberrations in keratoconus (KC) and pellucid marginal corneal degeneration (PMCD) and compare them to age-matched normal eyes using the pentacam system.
Materials and Methods:
This single-center, retrospective study was carried out at a tertiary eye hospital in Uttar Pradesh, India. The electronic medical records (EMR) of patients with KC and PMCD were reviewed. The demographic information and pentacam report include corneal dioptric power in the flattest (K1), steepest (K2), maximum keratometry (Kmax) for the 3 mm central zone, and best-fit sphere (BFS) for an analysis region of 8 mm diameter were collected. In addition, pentacam was used to gather anterior and posterior corneal higher-order aberration (HOA).
Results:
Three groups, control, KC, and PMCD, consisting of 229 eyes from 126 patients, were included. The control and KC group included 100 eyes with a mean age of 29.72 ± 8.59 years and 27.13 ± 5.51 years. The PMCD group included 29 eyes, and the mean age was 36.24 ± 14.73 years. Statistically significant differences between the control and KC groups were found in all parameters of curvature and elevation: K1, K2, Kmax, BFS, and thinnest location ([P < 0.0001], post hoc test). However, statistically significant differences were found in all parameters of curvature and elevation except K1 and Kmax (P > 0.001 between the control and PMCD groups. The anterior corneal total RMS HOA values were statistically significant between the control group and the KC group, between the control group and the PMCD group, and between the KC group and the PMCD group (P < 0.0001 for all). The anterior primary vertical coma Z (3, −1) and Horizontal coma Z (3, +1) values were only statistically significant between the control group and KC group, control group, and PMCD group (P < 0.0001).
Conclusion:
The higher levels of HOA, such as vertical coma, primary coma, spherical aberrations, and coma-like aberrations, were noted in KC and PMCD eyes compared to the control group. The HOA patterns varied between the KC and PMCD groups, likely due to differences in the positioning of the corneal apex. |
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| ISSN: | 0972-0200 2454-2784 |