Enhancing postoperative analgesia in carotid endarterectomy patients: The potential of ultrasound-guided carotid sheath block combined with superficial cervical plexus block: A randomised trial

Background and Aims: Carotid endarterectomy (CEA) is a common procedure conducted under regional anaesthesia, providing real-time cerebral function monitoring. Many different combinations of regional cervical blocks exist, and most offer adequate analgesia in intraoperative and postoperative recover...

Full description

Saved in:
Bibliographic Details
Main Authors: Anamarija Kruc, Lada Lijovic, Matteo Skrtic, Iva Pazur, Nikola Perisa, Tomislav Radocaj
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-09-01
Series:Indian Journal of Anaesthesia
Subjects:
Online Access:https://journals.lww.com/10.4103/ija.ija_834_23
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832590606295105536
author Anamarija Kruc
Lada Lijovic
Matteo Skrtic
Iva Pazur
Nikola Perisa
Tomislav Radocaj
author_facet Anamarija Kruc
Lada Lijovic
Matteo Skrtic
Iva Pazur
Nikola Perisa
Tomislav Radocaj
author_sort Anamarija Kruc
collection DOAJ
description Background and Aims: Carotid endarterectomy (CEA) is a common procedure conducted under regional anaesthesia, providing real-time cerebral function monitoring. Many different combinations of regional cervical blocks exist, and most offer adequate analgesia in intraoperative and postoperative recovery. This research compares a superficial cervical plexus block (SCB) alone and combined with an ultrasound (US)-guided carotid sheath block (CSB). The primary objective was to explore the length of the sensory block after combining SCB and CSB. Methods: Patients scheduled for nonemergency CEA surgery were randomised into two cohorts. The Subject group (28 participants) received US-guided CSB and SCB. The Control group (31 participants) received only an SCB. Both groups received 0.5% levobupivacaine (2 mg/kg) along with 2% lidocaine (2 mg/kg). The sensory block time and its initiation, analgesia and neutrophil-to-lymphocyte ratio (NLR) were recorded before and after the block. The numeric pain rating scale (NPRS) was used to evaluate analgesia every 2 h for 12 h post block. Analysis of variance, Mann–Whitney U or log-rank test was used to analyse the distinction of selected variables. Results: The demographic characteristics were comparable across the cohorts. The Subject group demonstrated a significantly accelerated onset of sensory block (P = 0.029) and an extended time to first analgesia (P = 0.003). The sensory block was also substantially extended in the Subject group (P = 0.040). Postoperative pain (NPRS ≥1) within the first 12 h was more recurrent in the Control group (P = 0.048). NLR showed minimal disparity between the groups (P = 0.125). Conclusion: Combining SCB and US-guided CSB effectively and safely extends postoperative analgesia for CEA surgery.
format Article
id doaj-art-64b571010b70487b9aa9fb80a1744f4d
institution Kabale University
issn 0019-5049
0976-2817
language English
publishDate 2024-09-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Indian Journal of Anaesthesia
spelling doaj-art-64b571010b70487b9aa9fb80a1744f4d2025-01-23T09:23:03ZengWolters Kluwer Medknow PublicationsIndian Journal of Anaesthesia0019-50490976-28172024-09-0168980180810.4103/ija.ija_834_23Enhancing postoperative analgesia in carotid endarterectomy patients: The potential of ultrasound-guided carotid sheath block combined with superficial cervical plexus block: A randomised trialAnamarija KrucLada LijovicMatteo SkrticIva PazurNikola PerisaTomislav RadocajBackground and Aims: Carotid endarterectomy (CEA) is a common procedure conducted under regional anaesthesia, providing real-time cerebral function monitoring. Many different combinations of regional cervical blocks exist, and most offer adequate analgesia in intraoperative and postoperative recovery. This research compares a superficial cervical plexus block (SCB) alone and combined with an ultrasound (US)-guided carotid sheath block (CSB). The primary objective was to explore the length of the sensory block after combining SCB and CSB. Methods: Patients scheduled for nonemergency CEA surgery were randomised into two cohorts. The Subject group (28 participants) received US-guided CSB and SCB. The Control group (31 participants) received only an SCB. Both groups received 0.5% levobupivacaine (2 mg/kg) along with 2% lidocaine (2 mg/kg). The sensory block time and its initiation, analgesia and neutrophil-to-lymphocyte ratio (NLR) were recorded before and after the block. The numeric pain rating scale (NPRS) was used to evaluate analgesia every 2 h for 12 h post block. Analysis of variance, Mann–Whitney U or log-rank test was used to analyse the distinction of selected variables. Results: The demographic characteristics were comparable across the cohorts. The Subject group demonstrated a significantly accelerated onset of sensory block (P = 0.029) and an extended time to first analgesia (P = 0.003). The sensory block was also substantially extended in the Subject group (P = 0.040). Postoperative pain (NPRS ≥1) within the first 12 h was more recurrent in the Control group (P = 0.048). NLR showed minimal disparity between the groups (P = 0.125). Conclusion: Combining SCB and US-guided CSB effectively and safely extends postoperative analgesia for CEA surgery.https://journals.lww.com/10.4103/ija.ija_834_23carotid endarterectomycarotid sheath blockcervical plexus blockpostoperative painregional anaesthesiaultrasound
spellingShingle Anamarija Kruc
Lada Lijovic
Matteo Skrtic
Iva Pazur
Nikola Perisa
Tomislav Radocaj
Enhancing postoperative analgesia in carotid endarterectomy patients: The potential of ultrasound-guided carotid sheath block combined with superficial cervical plexus block: A randomised trial
Indian Journal of Anaesthesia
carotid endarterectomy
carotid sheath block
cervical plexus block
postoperative pain
regional anaesthesia
ultrasound
title Enhancing postoperative analgesia in carotid endarterectomy patients: The potential of ultrasound-guided carotid sheath block combined with superficial cervical plexus block: A randomised trial
title_full Enhancing postoperative analgesia in carotid endarterectomy patients: The potential of ultrasound-guided carotid sheath block combined with superficial cervical plexus block: A randomised trial
title_fullStr Enhancing postoperative analgesia in carotid endarterectomy patients: The potential of ultrasound-guided carotid sheath block combined with superficial cervical plexus block: A randomised trial
title_full_unstemmed Enhancing postoperative analgesia in carotid endarterectomy patients: The potential of ultrasound-guided carotid sheath block combined with superficial cervical plexus block: A randomised trial
title_short Enhancing postoperative analgesia in carotid endarterectomy patients: The potential of ultrasound-guided carotid sheath block combined with superficial cervical plexus block: A randomised trial
title_sort enhancing postoperative analgesia in carotid endarterectomy patients the potential of ultrasound guided carotid sheath block combined with superficial cervical plexus block a randomised trial
topic carotid endarterectomy
carotid sheath block
cervical plexus block
postoperative pain
regional anaesthesia
ultrasound
url https://journals.lww.com/10.4103/ija.ija_834_23
work_keys_str_mv AT anamarijakruc enhancingpostoperativeanalgesiaincarotidendarterectomypatientsthepotentialofultrasoundguidedcarotidsheathblockcombinedwithsuperficialcervicalplexusblockarandomisedtrial
AT ladalijovic enhancingpostoperativeanalgesiaincarotidendarterectomypatientsthepotentialofultrasoundguidedcarotidsheathblockcombinedwithsuperficialcervicalplexusblockarandomisedtrial
AT matteoskrtic enhancingpostoperativeanalgesiaincarotidendarterectomypatientsthepotentialofultrasoundguidedcarotidsheathblockcombinedwithsuperficialcervicalplexusblockarandomisedtrial
AT ivapazur enhancingpostoperativeanalgesiaincarotidendarterectomypatientsthepotentialofultrasoundguidedcarotidsheathblockcombinedwithsuperficialcervicalplexusblockarandomisedtrial
AT nikolaperisa enhancingpostoperativeanalgesiaincarotidendarterectomypatientsthepotentialofultrasoundguidedcarotidsheathblockcombinedwithsuperficialcervicalplexusblockarandomisedtrial
AT tomislavradocaj enhancingpostoperativeanalgesiaincarotidendarterectomypatientsthepotentialofultrasoundguidedcarotidsheathblockcombinedwithsuperficialcervicalplexusblockarandomisedtrial