Sirt6 deficiency promotes senescence and age-associated intervertebral disc degeneration in mice
Abstract Intervertebral disc degeneration is a major risk factor contributing to chronic low back and neck pain. While the etiological factors for disc degeneration vary, age is still one of the most important risk factors. Recent studies have shown the promising role of SIRT6 in mammalian aging and...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-05-01
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| Series: | Bone Research |
| Online Access: | https://doi.org/10.1038/s41413-025-00422-3 |
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