Genetic genealogy of Y-chromosome in the Zhetiru tribe of the Kazakh population from Kazakhstan
IntroductionThe Y chromosome, transmitted exclusively through the paternal line, is a well-established tool for verifying genealogical data. The Kazakh tribe Zhetiru in Kazakhstan, comprising seven clans, has conflicting historical and genealogical narratives regarding its origin—either as a union o...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-03-01
|
| Series: | Frontiers in Genetics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fgene.2025.1516130/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850095745520107520 |
|---|---|
| author | Aigul Zhunussova Saltanat Tayshanova Alizhan Bukayev Ayagoz Bukayeva Baglan Aidarov Radik Temirgaliev Radik Temirgaliev Zhaxylyk Sabitov Zhaxylyk Sabitov Maxat Zhabagin Maxat Zhabagin |
| author_facet | Aigul Zhunussova Saltanat Tayshanova Alizhan Bukayev Ayagoz Bukayeva Baglan Aidarov Radik Temirgaliev Radik Temirgaliev Zhaxylyk Sabitov Zhaxylyk Sabitov Maxat Zhabagin Maxat Zhabagin |
| author_sort | Aigul Zhunussova |
| collection | DOAJ |
| description | IntroductionThe Y chromosome, transmitted exclusively through the paternal line, is a well-established tool for verifying genealogical data. The Kazakh tribe Zhetiru in Kazakhstan, comprising seven clans, has conflicting historical and genealogical narratives regarding its origin—either as a union of seven independent clans or as descendants of a single common ancestor. A detailed genetic investigation has not yet addressed this question.Methods350 male volunteers from the Zhetiru tribe were analyzed using 23 Y-STR loci and 17 Y-SNPs. We calculated genetic distances using Arlequin and STRAF, and explored genetic structure with median-joining networks using a comparative dataset of over 3,000 Kazakh individuals.ResultsAt the tribal level, haplotype diversity (0.997) and haplogroup diversity (0.91) are high. However, at the clan level, haplotypic diversity decreases, revealing clear founder effects in the main haplogroups of Kerderi (R1a1a), Kereit (N1a2), Tama (C2a1a3), and Teleu (J2a2). The genetic structures of Zhagalbaily, Ramadan, and Tabyn indicate additional sub-clan founders. The ages of key clusters suggest stable genetic lineages for over 1,000 years. Zhetiru clans do not form a distinct genetic cluster among Kazakh tribes but demonstrate genetic affinities with others.ConclusionThis study demonstrates the effective application of genetic genealogy approaches in verifying historical and genealogical records concerning the Zhetiru tribe and determining its origin from distinct, genetically independent clans. |
| format | Article |
| id | doaj-art-64b3cc4eeab9497e9eab2a4aa6af5a09 |
| institution | DOAJ |
| issn | 1664-8021 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Genetics |
| spelling | doaj-art-64b3cc4eeab9497e9eab2a4aa6af5a092025-08-20T02:41:23ZengFrontiers Media S.A.Frontiers in Genetics1664-80212025-03-011610.3389/fgene.2025.15161301516130Genetic genealogy of Y-chromosome in the Zhetiru tribe of the Kazakh population from KazakhstanAigul Zhunussova0Saltanat Tayshanova1Alizhan Bukayev2Ayagoz Bukayeva3Baglan Aidarov4Radik Temirgaliev5Radik Temirgaliev6Zhaxylyk Sabitov7Zhaxylyk Sabitov8Maxat Zhabagin9Maxat Zhabagin10Astana International University, Astana, KazakhstanAstana International University, Astana, KazakhstanNational Center for Biotechnology, Astana, KazakhstanNational Center for Biotechnology, Astana, KazakhstanNational Center for Biotechnology, Astana, KazakhstanResearch Institute for Jochi Ulus Studies, Astana, KazakhstanKazak Historical Society, Astana, KazakhstanResearch Institute for Jochi Ulus Studies, Astana, KazakhstanKazak Historical Society, Astana, KazakhstanNational Center for Biotechnology, Astana, KazakhstanDNK Shejire LLP, Astana, KazakhstanIntroductionThe Y chromosome, transmitted exclusively through the paternal line, is a well-established tool for verifying genealogical data. The Kazakh tribe Zhetiru in Kazakhstan, comprising seven clans, has conflicting historical and genealogical narratives regarding its origin—either as a union of seven independent clans or as descendants of a single common ancestor. A detailed genetic investigation has not yet addressed this question.Methods350 male volunteers from the Zhetiru tribe were analyzed using 23 Y-STR loci and 17 Y-SNPs. We calculated genetic distances using Arlequin and STRAF, and explored genetic structure with median-joining networks using a comparative dataset of over 3,000 Kazakh individuals.ResultsAt the tribal level, haplotype diversity (0.997) and haplogroup diversity (0.91) are high. However, at the clan level, haplotypic diversity decreases, revealing clear founder effects in the main haplogroups of Kerderi (R1a1a), Kereit (N1a2), Tama (C2a1a3), and Teleu (J2a2). The genetic structures of Zhagalbaily, Ramadan, and Tabyn indicate additional sub-clan founders. The ages of key clusters suggest stable genetic lineages for over 1,000 years. Zhetiru clans do not form a distinct genetic cluster among Kazakh tribes but demonstrate genetic affinities with others.ConclusionThis study demonstrates the effective application of genetic genealogy approaches in verifying historical and genealogical records concerning the Zhetiru tribe and determining its origin from distinct, genetically independent clans.https://www.frontiersin.org/articles/10.3389/fgene.2025.1516130/fullY-chromosomeSTR (short tandem repeat)haplotype diversitygenetic genealogyZhetiru tribeKazakh population |
| spellingShingle | Aigul Zhunussova Saltanat Tayshanova Alizhan Bukayev Ayagoz Bukayeva Baglan Aidarov Radik Temirgaliev Radik Temirgaliev Zhaxylyk Sabitov Zhaxylyk Sabitov Maxat Zhabagin Maxat Zhabagin Genetic genealogy of Y-chromosome in the Zhetiru tribe of the Kazakh population from Kazakhstan Frontiers in Genetics Y-chromosome STR (short tandem repeat) haplotype diversity genetic genealogy Zhetiru tribe Kazakh population |
| title | Genetic genealogy of Y-chromosome in the Zhetiru tribe of the Kazakh population from Kazakhstan |
| title_full | Genetic genealogy of Y-chromosome in the Zhetiru tribe of the Kazakh population from Kazakhstan |
| title_fullStr | Genetic genealogy of Y-chromosome in the Zhetiru tribe of the Kazakh population from Kazakhstan |
| title_full_unstemmed | Genetic genealogy of Y-chromosome in the Zhetiru tribe of the Kazakh population from Kazakhstan |
| title_short | Genetic genealogy of Y-chromosome in the Zhetiru tribe of the Kazakh population from Kazakhstan |
| title_sort | genetic genealogy of y chromosome in the zhetiru tribe of the kazakh population from kazakhstan |
| topic | Y-chromosome STR (short tandem repeat) haplotype diversity genetic genealogy Zhetiru tribe Kazakh population |
| url | https://www.frontiersin.org/articles/10.3389/fgene.2025.1516130/full |
| work_keys_str_mv | AT aigulzhunussova geneticgenealogyofychromosomeinthezhetirutribeofthekazakhpopulationfromkazakhstan AT saltanattayshanova geneticgenealogyofychromosomeinthezhetirutribeofthekazakhpopulationfromkazakhstan AT alizhanbukayev geneticgenealogyofychromosomeinthezhetirutribeofthekazakhpopulationfromkazakhstan AT ayagozbukayeva geneticgenealogyofychromosomeinthezhetirutribeofthekazakhpopulationfromkazakhstan AT baglanaidarov geneticgenealogyofychromosomeinthezhetirutribeofthekazakhpopulationfromkazakhstan AT radiktemirgaliev geneticgenealogyofychromosomeinthezhetirutribeofthekazakhpopulationfromkazakhstan AT radiktemirgaliev geneticgenealogyofychromosomeinthezhetirutribeofthekazakhpopulationfromkazakhstan AT zhaxylyksabitov geneticgenealogyofychromosomeinthezhetirutribeofthekazakhpopulationfromkazakhstan AT zhaxylyksabitov geneticgenealogyofychromosomeinthezhetirutribeofthekazakhpopulationfromkazakhstan AT maxatzhabagin geneticgenealogyofychromosomeinthezhetirutribeofthekazakhpopulationfromkazakhstan AT maxatzhabagin geneticgenealogyofychromosomeinthezhetirutribeofthekazakhpopulationfromkazakhstan |