The β-triketone, nitisinone, kills insecticide-resistant mosquitoes through cuticular uptake

The β-triketone, nitisinone, kills insecticide-resistant mosquitoes through cuticular uptake

Abstract Background Insecticide resistance in disease-transmitting arthropods of agricultural, veterinary, and public health significance poses a significant threat to vector control programs worldwide. Previous studies demonstrated that blood-feeding arthropod vectors experience high mortality when...

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Bibliographic Details
Main Authors: Zachary Thomas Stavrou-Dowd, George Parsons, Clair Rose, Faye Brown, Rosemary Susan Lees, Álvaro Acosta-Serrano, Lee Rafuse Haines
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Parasites & Vectors
Subjects:
Vector-borne diseases
Mosquitoes
Tarsal
4-Hydroxyphenylpyruvate dioxygenase
Nitisinone
Insecticide resistance
Online Access:https://doi.org/10.1186/s13071-025-06939-0
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