Effectiveness of aflibercept in treating bevacizumab resistant macular edema

Abstract Aim Method Prospective study on patients with macular edema secondary to diabetes mellitus, retinal vein occlusion or wet AMD. All the patients enrolled in the study had partial or no response to bevacizumab represented by mild or no improvement in macular thickness SD-OCT pictu...

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Bibliographic Details
Main Author: Hussain Khudair Yassin
Format: Article
Language:English
Published: university of basrah 2024-12-01
Series:Basrah Journal of Surgery
Subjects:
Online Access:https://bjsrg.uobasrah.edu.iq/article_185682_1b329e4e5a72a78e766bb123e1c9995c.pdf
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Summary:Abstract Aim Method Prospective study on patients with macular edema secondary to diabetes mellitus, retinal vein occlusion or wet AMD. All the patients enrolled in the study had partial or no response to bevacizumab represented by mild or no improvement in macular thickness SD-OCT pictures or less than 2 lines improvement in best corrected visual acuity before switching to intravitreal aflibercept. Results 40 patients selected regardless their age, sex, & diabetic control relatively, but all of them had macular edema resistant to repeated intravitreal bevacizumab injection anatomically & clinically. Most of patients showed good response to aflibercept intravitreal injection, either from the first or repeated injection. Conclusion Aflibercept show good functional & anatomical improvement in macular edema not responding to frequent bevacizumab injection. To evaluate the ability of aflibercept in the treatment of resistant macular edema after repeated intravitreal bevacizumab injection.
ISSN:1683-3589
2409-501X