Zearalenone Depresses Lactation Capacity Through the ROS-Mediated PI3K/AKT Pathway

Zearalenone Depresses Lactation Capacity Through the ROS-Mediated PI3K/AKT Pathway

The effects of zearalenone (ZEA), a fungal toxin in food and feed, remain unclear on the mammary gland and lactation. This study examines ZEA-induced damage in lactating mice and bovine mammary epithelial cells (MAC-T), focusing on the role of the phosphatidylinositol 3-kinase/protein kinase B (PI3K...

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Bibliographic Details
Main Authors: Hong Chen, Di Qiu, Xue Miao, Wenyue Yang, Qi He, Hao Ren, Luyao Zhang, Hongri Ruan, Jiantao Zhang, Na Zhang
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Animals
Subjects:
mammary gland
milk production
oxidative stress
proliferation
zearalenone
Online Access:https://www.mdpi.com/2076-2615/15/7/1050
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