Cryopyrin-Associated Periodic Syndromes (CAPS): Pathogenesis, Clinical Manifestations, and IL-1-Targeted Therapeutic Strategies

Cryopyrin-Associated Periodic Syndromes (CAPS): Pathogenesis, Clinical Manifestations, and IL-1-Targeted Therapeutic Strategies

Cryopyrin-associated periodic syndromes (CAPS) are a group of rare, genetically determined autoinflammatory diseases resulting from gain-of-function mutations in the NLRP3 gene. These mutations lead to constitutive activation of the inflammasome and overproduction of interleukin-1β and interleukin-...

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Main Authors: Joanna Nadaj, Bartosz Czyżewski, Anna Mariankowska, Anna Dróżdż, Weronika Posuniak, Michał Dorota, Karol Kozłowski, Oliwia Kawa, Wojciech Żywiec, Cezary Milczarek
Format: Article
Language:English
Published: Kazimierz Wielki University 2025-07-01
Series:Journal of Education, Health and Sport
Subjects:
Cryopyrin-Associated Periodic Syndromes
NLRP3
Anakinra
CINCA/NOMID
Muckle-Wells syndrome
Familial Cold Autoinflammatory Syndrome
Online Access:https://apcz.umk.pl/JEHS/article/view/61828
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