Systemic Oxidative Stress Correlates with Sarcopenia and Pruritus Severity in Primary Biliary Cholangitis (PBC): Two Independent Relationships Simultaneously Impacting the Quality of Life—Is the Low Absorption of Cholestasis-Promoted Vitamin D a Puzzle Piece?

Systemic Oxidative Stress Correlates with Sarcopenia and Pruritus Severity in Primary Biliary Cholangitis (PBC): Two Independent Relationships Simultaneously Impacting the Quality of Life—Is the Low Absorption of Cholestasis-Promoted Vitamin D a Puzzle Piece?

<b>Background:</b> Unlike other chronic liver disorders, in primary biliary cholangitis (PBC), systemic oxidative stress (SOS) worsens along with liver disease progression status (DPS), influencing muscle metabolism, muscle quantity (MQ), and itch pathways. Synergistically, cholestasis c...

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Bibliographic Details
Main Authors: Marcello Dallio, Mario Romeo, Fiammetta Di Nardo, Carmine Napolitano, Paolo Vaia, Lorenzo Ventriglia, Annachiara Coppola, Simone Olivieri, Marco Niosi, Alessandro Federico
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Livers
Subjects:
sarcopenia
cholestasis
pruritus
oxidative stress
Online Access:https://www.mdpi.com/2673-4389/4/4/45
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