Strategies for Optimizing Acute Burn Wound Therapy: A Comprehensive Review

Recent advancements in acute burn wound therapy are transforming the management of burn injuries, with a focus on improving healing times, graft integration, and minimizing complications. However, current clinical treatments face significant challenges, including the difficulty of accurately assessi...

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Main Authors: Andrei Cretu, Andreea Grosu-Bularda, Eliza-Maria Bordeanu-Diaconescu, Florin-Vlad Hodea, Vladut-Alin Ratoiu, Catalina-Stefania Dumitru, Mihaela-Cristina Andrei, Tiberiu-Paul Neagu, Ioan Lascar, Cristian-Sorin Hariga
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Medicina
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Online Access:https://www.mdpi.com/1648-9144/61/1/128
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author Andrei Cretu
Andreea Grosu-Bularda
Eliza-Maria Bordeanu-Diaconescu
Florin-Vlad Hodea
Vladut-Alin Ratoiu
Catalina-Stefania Dumitru
Mihaela-Cristina Andrei
Tiberiu-Paul Neagu
Ioan Lascar
Cristian-Sorin Hariga
author_facet Andrei Cretu
Andreea Grosu-Bularda
Eliza-Maria Bordeanu-Diaconescu
Florin-Vlad Hodea
Vladut-Alin Ratoiu
Catalina-Stefania Dumitru
Mihaela-Cristina Andrei
Tiberiu-Paul Neagu
Ioan Lascar
Cristian-Sorin Hariga
author_sort Andrei Cretu
collection DOAJ
description Recent advancements in acute burn wound therapy are transforming the management of burn injuries, with a focus on improving healing times, graft integration, and minimizing complications. However, current clinical treatments face significant challenges, including the difficulty of accurately assessing wound depth and tissue viability, which can lead to suboptimal treatment planning. Traditional closure methods often struggle with issues such as delayed wound closure, limited graft survival, inadequate tissue regeneration, and insufficient vascularization. Furthermore, managing infection and minimizing scarring remain persistent obstacles, impacting functional recovery and aesthetic outcomes. Key areas of innovation include advanced imaging techniques that enable more precise assessment of wound depth, size, and tissue viability, allowing for more accurate treatment planning. In addition, new closure strategies are being developed to accelerate wound closure, enhance graft survival, and address challenges such as tissue regeneration, vascularization, and infection prevention. These strategies aim to optimize both functional recovery and aesthetic outcomes, reducing scarring and improving the quality of life for burn patients. While promising, these emerging techniques require further research and clinical validation to refine their effectiveness and expand their accessibility. Together, these innovations represent a significant shift in acute burn care, offering the potential for more personalized, efficient, and effective treatments.
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publishDate 2025-01-01
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spelling doaj-art-64a17555f525445dbbc66dbdb8e19ff12025-01-24T13:40:45ZengMDPI AGMedicina1010-660X1648-91442025-01-0161112810.3390/medicina61010128Strategies for Optimizing Acute Burn Wound Therapy: A Comprehensive ReviewAndrei Cretu0Andreea Grosu-Bularda1Eliza-Maria Bordeanu-Diaconescu2Florin-Vlad Hodea3Vladut-Alin Ratoiu4Catalina-Stefania Dumitru5Mihaela-Cristina Andrei6Tiberiu-Paul Neagu7Ioan Lascar8Cristian-Sorin Hariga9Department 11, Discipline Plastic and Reconstructive Surgery, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment 11, Discipline Plastic and Reconstructive Surgery, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaClinic of Plastic Surgery and Reconstructive Microsurgery, Clinical Emergency Hospital of Bucharest, 014461 Bucharest, RomaniaDepartment 11, Discipline Plastic and Reconstructive Surgery, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment 11, Discipline Plastic and Reconstructive Surgery, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment 11, Discipline Plastic and Reconstructive Surgery, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment 11, Discipline Plastic and Reconstructive Surgery, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment 11, Discipline Plastic and Reconstructive Surgery, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment 11, Discipline Plastic and Reconstructive Surgery, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment 11, Discipline Plastic and Reconstructive Surgery, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaRecent advancements in acute burn wound therapy are transforming the management of burn injuries, with a focus on improving healing times, graft integration, and minimizing complications. However, current clinical treatments face significant challenges, including the difficulty of accurately assessing wound depth and tissue viability, which can lead to suboptimal treatment planning. Traditional closure methods often struggle with issues such as delayed wound closure, limited graft survival, inadequate tissue regeneration, and insufficient vascularization. Furthermore, managing infection and minimizing scarring remain persistent obstacles, impacting functional recovery and aesthetic outcomes. Key areas of innovation include advanced imaging techniques that enable more precise assessment of wound depth, size, and tissue viability, allowing for more accurate treatment planning. In addition, new closure strategies are being developed to accelerate wound closure, enhance graft survival, and address challenges such as tissue regeneration, vascularization, and infection prevention. These strategies aim to optimize both functional recovery and aesthetic outcomes, reducing scarring and improving the quality of life for burn patients. While promising, these emerging techniques require further research and clinical validation to refine their effectiveness and expand their accessibility. Together, these innovations represent a significant shift in acute burn care, offering the potential for more personalized, efficient, and effective treatments.https://www.mdpi.com/1648-9144/61/1/128burn woundwound healingimaging techniquestherapeutic strategiesnovel therapiesskin substitutes
spellingShingle Andrei Cretu
Andreea Grosu-Bularda
Eliza-Maria Bordeanu-Diaconescu
Florin-Vlad Hodea
Vladut-Alin Ratoiu
Catalina-Stefania Dumitru
Mihaela-Cristina Andrei
Tiberiu-Paul Neagu
Ioan Lascar
Cristian-Sorin Hariga
Strategies for Optimizing Acute Burn Wound Therapy: A Comprehensive Review
Medicina
burn wound
wound healing
imaging techniques
therapeutic strategies
novel therapies
skin substitutes
title Strategies for Optimizing Acute Burn Wound Therapy: A Comprehensive Review
title_full Strategies for Optimizing Acute Burn Wound Therapy: A Comprehensive Review
title_fullStr Strategies for Optimizing Acute Burn Wound Therapy: A Comprehensive Review
title_full_unstemmed Strategies for Optimizing Acute Burn Wound Therapy: A Comprehensive Review
title_short Strategies for Optimizing Acute Burn Wound Therapy: A Comprehensive Review
title_sort strategies for optimizing acute burn wound therapy a comprehensive review
topic burn wound
wound healing
imaging techniques
therapeutic strategies
novel therapies
skin substitutes
url https://www.mdpi.com/1648-9144/61/1/128
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